重庆大学二级教授、弘深杰出学者，国家级人才，国家科技创新重大专项首席科学家，重庆市科技创新领军人才、重庆市五四青年奖章、重庆市创新争先奖获得者，第六届重庆市政协委员，医学院党委教工三支部书记。主要研究方向为重要疾病智慧预警与数字化诊疗研究，包括柔性可穿戴研究、合成生物学研究、重要疾病早期标志物筛选与检测、疾病现场快速检测、生物传感、微生物防控以及肿瘤诊疗一体化的基础和应用基础研究等。在Sci Transl Med，The Lancet Microbe，Nat Commun等CNS子刊和行业顶刊发表高水平学术论文100余篇，5篇ESI高被引。申报国际PCT专利6项，获国家发明专利授权36件。

先后主持国家杰青、重点专项、面上等课题，国家科技创新2030“四大慢病”重大专项、“主动健康”国家重点研发计划课题、云南省重点研发项目、重庆市杰青等科研项目30余项。入选全球前2%顶尖科学家榜单，获国家科技进步二等奖（排5）、重庆市技术发明一等奖（排1）、重庆市科技进步一等奖（排1、排3）、中华医学科技奖青年奖（排1）、中国发明协会创新创业成果一等奖（排1）、中国商业联合会科技进步一等奖（排1）等省部级以上奖项10余项。

担任国际临床化学和实验医学联盟（IFCC）C-EMC委员、国家卫健委能力建设和继续教育检验医学专委会副主任委员、中国医疗保健国际交流促进会检验医学分会主任委员、中华医学会检验分会委员/分子诊断学组副组长、中国医师协会检验医师分会委员/临床实验室管理学组副组长、重庆市医师协会常务委员、重庆市医学会检验分会副主任委员、重庆市科普研究会理事长、重庆市科技青年联合会副主席、重庆市科普作家协会副理事长、“高致病性病原微生物”重庆市重点实验室学术委员会主任委员等。长期担任国家科技部、国家基金委、教育部、国家卫健委等部委人才项目和各省市级科研项目的评审专家。

1.国际临床化学和实验医学联盟（IFCC）C-EMC委员

2.国家卫健委能力建设和继续教育检验医学专委会副主任委员

3.中国医疗保健国际交流促进会检验医学分会主任委员

4.中华医学会检验医学分会分子诊断学组副组长

5.中国医师协会检验医师分会临床实验室管理学组副组长

6.中国生物化学与分子生物学会生物技术专业分会副主任委员

7.中国毒理学会临床检验毒理学专业委员会常务委员

8.重庆市医学会检验分会委员会副主任委员

9.首届中国抗癌协会（CACA）指南进校园工作委员会 委员

10.重庆市医师协会常务理事

11.重庆市医学会医学科学研究管理学分会副主任委员

12.重庆市医学计量技术委员会副主任委员

13.重庆市科技青年联合会副主席

14.重庆市交叉医学专业教学指导委员会委员

15.美国临床化学协会（AACC） 会员

16.美国化学协会（ACS） 会员

1.2011.06－2012.06，美国中佛罗里达大学，博士后

2.2011.03－2011.06，美国乔治亚医学院，访问学者

3.2005－2008，中国人民解放军第三军医大学，临床检验诊断学，博士

4.2002－2005，中国人民解放军第三军医大学，临床检验诊断学，硕士

5.1997－2002，中国人民解放军第三军医大学，检验医学，学士

1.2025.11－至今，重庆市医学科学院副院长，教授、博导

2.2024.08－至今，重庆大学，医学院副院长/附属人民医院检验科主任，教授、博导

3.2024.08－至今，重庆市临床检验中心副主任，教授、博导

4.2024.03－2024.08， 重庆大学，医学院副院长/科学技术发展研究院副院长，教授、博导

5.2023.09－2023.09，国家教育行政学院，高校高层次人才国情研修

6.2020.12－2021.01， 中国科协党校青年科技领军人才国情研修

7.2019.06－至今，重庆大学，医学院公共实验中心主任，教授、博导

8.2017.12－2019.06， 重庆大学， 生物工程学院，教授、博导

9.2008.09－2017.11，第三军医大学，第一附属医院，副教授/副主任医师、博导

团队主要研究方向：

1.重大疾病早期智慧预警研究

围绕老年慢性疾病、老年健康、传染性疾病、肺相关疾病的预警和干预，以老年群体健康特性及常见病相关发病机理、标志物为依托，于国际上率先提出整合液体活检理念（Theronostics,2020，封面），建立了脓毒症预警分层模型（Nat Commun,2025），基于新型纳米材料解决了脓毒症精准诊疗难题（Sci Transl Med,2025）。基于生物信息学、机器学习等技术手段进行老年人群的疾病风险及全人群肺癌风险预测，多维度开展老年慢性疾病的早期预警和干预相关研究，研制可穿戴设备实现老年性疾病的远程监控及肺部疾病的智慧预警。基于AI技术建立我国西部地区首个基于神经网络模型新冠预警系统。

2.现场快速检测研究

针对严重创伤早期现场救治需求，开展快速扩容及疾病标志物检测研究。以血型检测为例，首创30秒血型快速检测纸基微流控，可在2min完成16种血型同步检测（Sci Transl Med, 2017，封面），相关研究成果被Transfus Med Rev评为2017年度全球输血领域最大突破之一，入围2017年中国十大医学进展。后又建立了基于手机二维码智能读取技术（授权国际专利三项，ACS Nano, 2021）。基于纳米探针和DNA自组装技术，解决了攻克生物分子早期超敏识别、信号放大的问题（ACS Nano, 2024; Biosens Bioelectron, 2024; Anal Chem, 2020, 2021, 2022, 2023, 2024），为疾病快速检测提供了坚实的技术保障。

3.全生命周期智慧诊疗研究

针对慢性病全周期实时动检测难题，研发基于可降解生物材料的柔性电子器件与仿生微针贴片，通过光电集成技术实现便携式人机交互，对多种慢性病生物标志物进行了远程的实时监测和采集。创新性地构建基于MXene掺杂拓扑凝胶传感器，突破了信息存储与运输转换平衡的瓶颈问题，为慢性病患者的个性化治疗和健康监测提供了全新的手段与思路（ACS Nano, 2024）。针对肿瘤耐药、精准诊断等方向，建立了一系列新策略、新方法（Bioactive Materials,2025；Biomaterial,2025；ACS Nano,2025）。

4.微生物感染的精准防控

基于分子生物学、细胞生物学、生物信息学等技术研究微生物感染致病过程中的微生物与宿主互作机制（Nat Commun, 2023; eBioMedicine, 2023;Lancet Microbe,2025）；基于核酸扩增、DNAzyme等分子自组装等策略，构建不依赖大型设备的外泌体分离、分析新方法，精准甄别微生物感染类型，实现感染性疾病的精准防控。针对自然界中新发现的动物源头甲肝病毒（PNAS, 2015），率先开展了其3ABC蛋白酶与宿主MAVS免疫屏障的分子互作及共进化研究，发现了蝙蝠甲肝病毒蛋白酶高效破坏人类MAVS蛋白的作用机理（J Hepatol, 2019），并进一步探索了该逃逸策略在甲肝病毒跨种传播致病过程中生物学重要性（J Hepatol, 2023）。

教学课程：

《学术规范与研究生论文写作指导》《分子医学前沿》《生物芯片》《军事检验医学》《实验诊断学》《仿生学》《微生物资源与利用》《生物医学导论》《细胞生物学前沿与进展》等

指导学生：

招生资格：硕士研究生、博士研究生（直博生）、弘深青年教师（博士后）

招生专业：临床医学（临床检验诊断学）、基础医学（分子医学）、生物与医药

大学生竞赛：本科生（SRTP项目、互联网+、挑战杯等）

中学生：英才计划、雏鹰计划

1.《Exploration》Editorial board member

2.《Interdisciplinary Medicine》Editorial board member

3.《Extracellular Vesicles and Circulating Nucleic Acids》Editorial board member

4.《Aging Medicine》Editorial board member

5.《Military Medical Research》Young member of the editorial board

6.《Medicine Bulletin》Associate Editor

7.《Journal of Biological Methods》Associate Editor

8.《Future Medicine》Associate Editor

9.《Medicine Advances》Editorial board member

10.《检验医学与临床》第八届编辑委员会 主编

11.《中华临床实验室管理电子杂志》副主编

12.《医学参考报》检验医学专刊 副主编

13.《中华检验医学杂志》第十届编辑委员会 编委

14.《中国医学前沿杂志（电子版）》编辑委员会 编委

15.《检验医学》第八届编辑委员会编委

1.重庆市创新争先奖（2025）

2.重庆实验外国语学校科学副校长（2024）

3.全国优秀科普工作者（2024）

4.重庆市科普研究会理事长（2023）

5.重庆市科普作家协会副理事长（2023年）

6.重庆南渝中学成长导师、重庆大学附属七中梦想导师（2022）

7.重庆市一中集团71中学科学副校长（2024）

8.重庆市北碚区朝阳小学科学教育顾问（2024）

9.首届川渝科普大会最具有影响力的川渝科普榜样（2023）

10.“典赞·科普中国”年度科普人物提名奖（2023、2022连续两年）

11.重庆市青少年科技教育专家（2022）

12.罗阳教授科普工作室志愿者支队（2021年）

13.罗阳教授科普工作室负责人（2020年）

2026年

[1] Qing Hao,Tao Zhou,Huayun Yan,Zhixiang Ren,Wei Mao,Li-Bin Huang,Yue-yun Chen,Yuelan Wang,Minqin Xiao,Yajiao He,Xuyang Xia,Jing Wu,Wei-Han Zhang,Hai-Ning Chen,Maoxiang Qian,Feng Zhang,Li Yang,Lunzhi Dai,Huiyuan Zhang,Canhua Huang,Yang Shu,Yu Xu*,Yang Luo*,Yong Peng*,Heng Xu*.A pan-cancer single cell landscape reveals heterogeneity and functional diversity of double-negative T cells.Molecular Cancer .2026;25(1):24(IF:33.9).DOI:10.1186/s12943-025-02548-8.

[2] Xiaolin Hu,Jie Xie,Xinlin Guo,Liangting Wang,Zhengheng Yu,Xiaopei Qiu,Heng Li,Kang Wang,Xiaoxing Wang,Mingxuan Song,Junsong Guo,Wei Gu,Sergio Bernardini,Chaoyong Yang*,Hong Zhang*,Yang Luo*.Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping.Advanced Science.2026 (IF:14.1).DOI:10.1002/advs.202518307.

[3] Heng Li,Yusheng Qin,Jianhong Zhang,Xinlin Guo,Xiaolin Hu,Danlei Sun,Yue Zhao,Sergio Bernardini,Daqian Xu,Peng Jiang*,Hong Zhang*,Yang Luo*.A foam cell-targeted lipophagy restoration strategy stabilizes vulnerable atherosclerotic plaques.Bioactive Materials.2026;61:879-899(IF:20.3).DOI: 10.1016/j.bioactmat.2026.02.041.

[4] Dongdong Liu*, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang*, Ling Zhu*, Yang Luo*.Lymph-based liquid biopsy: Current progress and future potential.Interdisciplinary Medicine.2026;3(3):e20240101(IF:13.6，COVER).DOI:10.1002/inmd.70092.

[5] Xianfeng Wang,Liyuan Meng,Dapeng Zhou,Bingqing Zhao,Yuanhang Yu,Fengwu Lin,Mingzhu Gao*,Gongle Shen*,Yang Luo*.N, S, P co-doped carbon dots with yellow emission for high-sensitivity detection and bioimaging of α-lipomycin in salt-sensitive hypertension.Chemical Engineering Journal. 2026;527(C):171548(IF:13.2).DOI: 10.1016/j.cej.2025.171548.

[6] Zhizhi Xiang,Chuhang Wei,Shu Zhu,Shan Liu,Renjun Zhang,Xuehao Tong,Zixu Wang,Jiaxin Deng,Xiang Zhang,Lingfeng Zhong,Ruini Sun,Yahan Hou,Cheng Jiang*,Yuchan Zhang*,Yang Luo*,Guangchao Zang*. From detection to mechanistic insight: Electrochemiluminescence as a universal platform for reaction kinetics.Biosensors and Bioelectronics.2026;295(C)(IF:10.5). DOI:10.1016/j.bios.2025.118279.

[7] Kang Wang,Junhui Zhang,Wenjing Liu,Liang Kong,Heng Li,Laixian Zhou,Jianhong Zhang,Xiaolin Hu,Xiaopei Qiu,Xiaoxing Wang,Wei Gu*,Hong Zhang*,Yang Luo*.Bioresponsive Dual Microspheres Embedded in a Hydrogel: A Sequentially Triggered Strategy for Regulating Diabetic Wound Healing.Archiv der Pharmazie.2026;(IF:3.6).DOI:10.1002/adhm.202505948.

[8] Yuqing Zhao,Shijing Tang,Jingying Zhou,Yang Luo*,Liang Duan*.Migrasomes: a journey from biogenesis to multifaceted roles in health and disease.Biomarker Research.2026;14(1):31(IF:11.5). DOI:10.1186/s40364-026-00904-4.

[9] Zhongwen Hu,Guiling Yan,Junhong Li,Yuan Yuan,Hong Zhang,Yuchao Zhong,Yuanyuan Peng,Wenjia Zhang,Xiaoyan Su,Changchun Niu*,Yang Luo*.Sphinganine-phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation.VIEW.2026；（IF：8.5）.DOI:10.1002/viw.20250217.

[10] Meng Pan,Huanyu Li,Hao Guo,Shiting Luo,Jianxuan Yao,Mingxin Zhang*,Yang Luo*,Xiaoyan Shi*.Roumudan decoction attenuates hepatic fibrosis by suppressing the Warburg effect via inhibiting key glycolytic proteins.Journal of Ethnopharmacology.2026;356:120862(IF:5.4).DOI:10.1016/j.jep.2025.120862.

[11] Qianqian Wu,Yican Li,Ruyan Niu,Xing Wang,Yufang Zhang,Yao Ma,Zhixin Cha,Yao Luo,Xin Cui,Jichun Yang,Zheng Chen,Zhizeng Wang,Xiaohui Chen*,Yang Luo*.Self-protected circular DNAzyme for integrated enrichment and quantification of small extracellular vesicles.Analyst .2026;(IF:3.3).DOI: 10.1039/d5an01340b.

2025年

[1] Guangchao Qing, Yuxuan Zhang, Yongchao Wang, Xianlei Li, Ting Luo, Fuxue Zhang, Qiankun Ni, Runjing Hu, Shaobo Shan, Hong Zhang, Rui Yuan, Yaling Gan, Xing-Jie Liang*, Yang Luo*. FcγR-targeted tuftsin clusters rejuvenate macrophages in preclinical sepsis–associated secondary infection. Science Translational Medicine. 2025;17(830): eadv0313(IF:14.6). DOI: 10.1126/scitranslmed.adv0313.

[2] Heng Li, Jianhong Zhang, Kang Wang, Sergio Bernardini, Hong Zhang*, Yang Luo*. Human metapneumovirus prevention within reach: advances in vaccines and monoclonal antibodies. The Lancet Microbe.2025;101303 (IF:20.4). DOI: 10.1016/j.lanmic.2025.101303.

[3] Li Zhu, Zengtian Chen, Hong Zhang, Hongjun Chen, Lanqi Liu, Wei Yu, Kai Wu, Yijin Chen, Xingyu Tao, Zefeng Yu, Linhui Shi, Jialian Wang, Fan Zhang, Jiaying Shen, Fen Liu, Chongke Hu, Yangguang Ren, Tzu-Ming Liu, Yang Luo*, Fei Guo*, Bailin Niu*. Explainable AI unravels sepsis heterogeneity via coagulation-inflammation profiles for prognosis and stratification. Nature Communications. 2025; 16(1):10396 (IF:15.7). DOI: 10.1038/s41467-025-65365-z.

[4] Jintao Zheng, Xiaohong Jiang, Shiyao Bai, Minchao Lai, Jiacheng Yu, Mingxi Chen, Runzhi Zhou, Yue Jia, Haoyang Yan, Zheng Liang, Dian Wang, Chuyan Wu, Shan Liu*, Chenzhong Li, Jinguang Yang*, Yang Luo*, Cheng Jiang*, Keying Guo*. Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers. Advanced Materials. 2025; 37(37): e2505262 (IF:26.8). DOI: 10.1002/adma.202505262.

[5] Xiaohui Wang, Zhiyuan Xu, Jian Wang, Chunrong Wu, Lin Zhang, Chengyuan Qian, Yang Luo*, Yanjuan Gu*, Wing-Tak Wong*, and Debing Xiang*. A mitochondria-targeted biomimetic nanomedicine capable of reversing drug resistance in colorectal cancer through mitochondrial dysfunction. Advanced Science. 2025; 12(13): e2410630. (IF: 14.3). DOI: 10.1002/advs.202410630.

[6] Jichun Yang*, Yuhan Wang, Kang Wang, Xiaohui Chen, Yilin Liu, Qianqian Wu, Hengyi Chen, Guangchao Qing, Yunqian Fu, Xin Cui, Yao Luo, Sitong Wang, Guoliang Duan, Mingyang Zhang, Yimin Jia, Xinghong Hu, Zhizeng Wang, Xing-Jie Liang*, Huaping Xu*, Yang Luo*. A Spatiotemporally Controllable DNA Hydrogel Mesh for Focused Antimetastasis Therapy of Cancer. ACS Nano 2025; 19(34): 31183-31200. (IF:16). DOI: 10.1021/acsnano.5c10067.

[7] Chunxia Chen, Jingjing Ma, Shujie Duan, Menghan Xue, Zhan Yang, Ziwei Ma, Jianing Ji, Yuanfang Ma, Guangchao Qing, Keying Guo, Wei Wu*, Tianfeng Chen*, Zhizeng Wang*, Yang Luo*. Mitigation of Ischemia/Reperfusion Injury via Selenium Nanoparticles: Suppression of STAT1 to Inhibit Cardiomyocyte Oxidative Stress and Inflammation. Biomaterials. 2025; 318:  123119 (IF: 12.9). DOI: 10.1016/j. biomaterials.2025.123119.

[8] Zhonghao Li, Zhihan Cai, Yuhan Wang, Yuliang Liu, Guifeng Li, Xi Yang, Ming Deng, Yu-Cheng Chen*, Jichun Yang*, Yang Luo*, Chaoyang Gong*, Tao Zhu*. Laser-Emission Vibrational Microscopy of Microdroplet Arrays for High-Throughput Screening of Hyperlipidemia. Light: Science & Applications. 2025;12, 1623557 (IF:23.4, COVER). DOI: 10.1038/s41377-025-02015-5.

[9] Jichun Yang, Qianqian Wu, Yunqian Fu, Xiaohui Chen, Hengyi Chen, Yuhan Wang, Xiang Wu, Xin Cui, Sitong Wang, Yao Luo, Yufang Zhang, Yican Li, Yan Zhao, Zhixin Cha, Linke Shi, Xianlong Jiao*, Fang Li*, Yang Luo*. Turmeric extracellular vesicles-derived “all-in-one” nanoagent enables full-cycle synergistic immunomodulation of lung cancer. Bioactive Materials. 2025; 56: 666-681 (IF:20.3). DOI: 10.1016/j.bioactmat.2025.10.017.

[10] Qianqian Wu, Xiaohui Chen, Sitong Wang, Xing Wang, Zhixin Cha, Hengyi Chen, Yangguang Ren, Yao Luo, Xin Cui, Yan Zhao, Yufang Zhang, Yican Li, Zhongyao Ge, Sergio Benardini, Zhizeng Wang*, Jichun Yang*, Yang Luo*. Well-defined Electronic Configuration Cyano-Bridged Bimetallic Nanozyme for Cancer Catalytic-Immunotherapy. Biomaterials. 2025; 123868(IF: 12.9). DOI: 10.1016/j.biomaterials.2025.123868.

[11] Chunxia Chen, Zhan Yang, Yangguang Ren, Menghan Xue, Jinbo Wu, Jianing Ji, Yan Zhao, Ruyan Meng, Yao Ma, Xiaoquan Li, Yonghong Wang, Xiaohui Chen, Ziwei Li *, Xiaogang Lin*, Zhizeng Wang*, Yang Luo*. Precision antibody orientation on gold nanoparticles via pH control enables clinic-grade lateral flow detection of acute myocardial infarction. Nano Materials Science. 2025;2589-9651 (IF:17.9). DOI: 10.1016/j.nanoms.2025.11.003.

[12] Jichun Yang*, Yuhan Wang, Yunqian Fu, Sitong Wang, Yao Luo, Xin Cui, Chenyu Sun, Jianing Ji, Jiaxi Mo, Yang Wang, Yilin Liu, Xinghong Hu, Xiaohui Chen, Yimin Jia*, Yang Luo*.  Plant extracellular vesicles: A promising bionic medicine platform for disease treatment and drug delivery. Interdisciplinary Medicine. 2025; e20240101. (IF:13.6). DOI: 10.1002/INMD.20240101.

[13] Xiaohui Chen, Haixia Liu, Ningyu Ma, Chenyu Sun, Yican Li, Hengyi Chen, Qianqian Wu, Zhizeng Wang, Jichun Yang*, Guoxiang Liu*, and Yang Luo*. Precise Determination of CpG Methylation through Entropy-Driven Cascade Circuit. Analytical Chemistry. 2025; 97(25):  13325-13334 (IF:6.7). DOI: 10.1021/acs.analchem.5c01453.

[14] Hong Zhang*, Xiaolin Hu, Xudong Bao, Wei Tu, Qiwu Wan, Zhengheng Yu, Jie Xie, Xiaopei Qiu, Wei Gu, Zhaoli Gao, Yongzhong Wang, Chuanxin Wang*, Yang Luo*. Commercial Strip‐Inspired One‐Pot CRISPR‐Based Chip for Multiplexed Detection of Respiratory Viruses. Small Methods. 2025;9(1), 2570001 (IF:9.1, COVER). DOI: 10.1002/smtd.202400917.

[15] Chunxia Chen, Shujie Duan, Jianing Ji, Mengli Wu, Zhan Yang, Mengyang Cai, Menghan Xue, Lanju Wang, Rui Chen, Sima Yaron, Keying Guo*, Sergio Benardini*, Zhizeng Wang*, Yang Luo*. Structured protein probes modified with selenium nanoparticle for 1-minute measurement of SARS-CoV-2 antigen. Biosensors and Bioelectronics. 2025; 268: 116878 (IF:10.5). DOI: 10.1016/j.bios.2024.116878.

[16] Jichun Yang*, Chenyu Sun, Yufang Zhang, Jianing Ji, Yuhan Wang, Qianqian Wu, Yan Zhao, Zhixin Cha, Yican Li, Xin Cui, Yao Luo, Sitong Wang, Zhizeng Wang, Sergio Benardini, Xiaohui Chen*, Yang Luo*. Endogenous stimuli-derived self-assembled DNA tetrahedron (MESH) for precise imaging and activatable mitochondrial interference. Chemical Engineering Journal. 2025; 524: 169613 (IF:13.2). DOI: 10.1016/j.cej.2025.169613.

[17] Yajie Zhao, Chuting Xiao, Lanjie Ren, Yuanfang Ma, Yanyan Wang*, Hailong Zhang*,  Yang Luo*. The Dual Nondestructive Amplification Strategy Realizes the Ultrasensitive Detection of Soluble TRAIL in Human Plasma. Analytical Chemistry. 2025; 97(45): 25295-25303 (IF:6.7). DOI: 10.1021/acs.analchem.5c05121.

[18] Tingting Zhou, Gongle Shen, Linling Zhong, Genchang Chen, Liyuan Meng, Wenyin He, Jing Liu, Sen Yang*, Yang Luo*, Xianfeng Wang*. crRNA array-mediated CRISPR/Cas12a coupling with dual RPA for highly sensitive detection of Streptomyces aureofaciens Tu117 from hypertension with multi-signal output. Biosensors and Bioelectronics. 2025; 282: 117493 (IF:10.5).  DOI:10.1016/j.bios.2025.117493.

[19] Qiao Chen, Xu Yang, Yao Yu, Xinmei Duan, Rongrong Ni, Guojing Song, Li Zhu, Yuan Zhong, Kai Qu, Xian Qin, Kun Zhang*, Yang Luo*, Wei Wu*. Biomimetic Cerium-Assisted Supra-Carbon Dots Assembly for Reactive Oxygen Species-Activated Atherosclerosis Theranostic.  Small. 2025; 2408980.  (IF: 13).  DOI: 10.1002/smll.202408980.

[20] Zhizhi Xiang, Chuhang Wei, Shu Zhu, Shan Liu, Renjun Zhang, Xuehao Tong, Zixu Wang, Jiaxin Deng, Xiang Zhang, Lingfeng Zhong, Ruini Sun, Yahan Hou, Cheng Jiang*, Yuchan Zhang*, Yang Luo*, Guangchao Zang*. From Detection to Mechanistic Insight: Electrochemiluminescence as a Universal Platformfor Reaction Kinetics. Biosensors and Bioelectronics. 2025; 295, 118279. (IF:10.5). DOI: 10.1016/j.bios.2025.118279.

[21] Jinmin Zhou, Houxuan Li, Shuhong Li, Yuhan Wang, He Wang, Jie Li, Yiyao Hu, Jinlin Song*, Jichun Yang*, Yang Luo*. Convertible Hydrogel Injection Sequentially Regulates Diabetic Periodontitis. ACS Biomaterials Science & Engineering. 2025; 11(2): 916-929 (IF:5.5). DOI:  10.1021/acsbiomaterials.4c01784.

[22] Kang Wang, Wenjing Liu, Jingzhi Wu, Heng Li, Hai Peng, Junhui Zhang, Ke Ding, Xiaoxing Wang, Chengyi Hou*, Hong Zhang*, Yang Luo*. Smart Wearable Sensor Fuels Noninvasive Body Fluid Analysis. ACS Applied Materials & Interfaces. 2025; 17(9): 13279-13301 (IF:8.5). DOI: 10.1021/acsami.4c22054.

[23] Shuai Liu, Yi Li, Lin Quan, Hai-Xia Liu*, Yang Luo*, Yong-Zhong Wang*. Enhancing cellulase biosynthesis of Bacillus subtilis Z2 by regulating intracellular NADH level. iScience. 2025; 28(5): 112341 (IF:4.1). DOI:10.1016/j.isci.2025.112341.

[24] Jiaxi Mo, Yan Zhao, Chenyu Sun, Mingtao Li, Hengyi Chen, Yufang Zhang, Xiaohui Chen, Xinlin Guo, Zhizeng Wang, Yonghong Wang, Jichun Yang*, Yang Luo*. Strand displacement-driven CRISPR/Cas12a framework enables precise identification of low-abundance point mutations. VIEW. 2025; 6(4)20250047 (IF:8.5). DOI: 10.1002/viw.20250047.

[25] Ling Yan, Zhenxin Wang, Yajie Yin, Changchun Niu*, Yang Luo*. Coupling enzymatic digestion with nanopore sensing for low-abundance EGFR-L858R mutation detection. Frontiers in Bioengineering and Biotechnology. 2025;13: 1602494 (IF: 4.8).DOI: 10.3389/fbioe.2025.1602494.

[26] Qiongwen Hu, Xiaocheng Cheng, Ying Lan, Huxin Lei, Changchun Niu*, Yang Luo*. Serum uric acid predictive value and prognostic impact in rheumatoid arthritis' associated interstitial lung disease. Frontiers in Medicine. 2025;12: 1623557 (IF:3). DOI: 10.3389/fmed.2025.1623557.

[27] Yuanyuan Guo, Kai Shen, Zhijie Li, Changchun Niu*, Yang Luo*. MiR-147b-3p promotes osteogenesis by targeting NDUFA4 and PI3K/AKT pathway. Journal of Orthopaedic Surgery and Research . 2025; 20(1), 235 (IF:2.8). DOI: 10.1186/s13018-025-05598-2.

[28] Xiaoxing Wang, Hui Xiao, Yinghui Zhao， Pingyun Li， Xiaolin Hu， Xiaopei Oiu， Chenglei Luo， Jie Luo， Kang Wang, Wei Gu, Huanyu Cheng*, Hong Zhang*, Yang Luo*. Toward Omni Healthcare: Wearable Technologies for Noncommunicable Disease Dynamic Monitoring. Medical Bulletin. 2025; 00:1–15 (IF:5.2). DOI:10.1002/mdb2.70014.

[29] 重庆市科普研究会，中华医学会检验医学分会，中国毒理学会，等.全生命周期主动健康科普框架中国专家共识.检验医学与临床，2025, 22(02): 145-150. DOI: 10.3969/j.issn.1672-9455.2025.02.001.

2024年

[1] Jiabei Luo, Hong Zhang, Chuanyue Sun, Yangmin Jing, Kerui Li, Yaogang Li, Qinghong Zhang, Hongzhi Wang,Yang Luo*, and Chengyi Hou*. Topological MXene Network Enabled Mixed IonElectron Conductive Hydrogel Bioelectronics. ACS Nano. 2024;18, 5, 4008-4018 (Nature Index, IF: 17.10). DOI: 10.1021/acsnano.3c06209.

[2] Xinmei Duan, Xu Yang, Nianlian Mou, Yu Cao, Zhigui He, Li Zhu, Yuan Hong, Kun Zhang, Kai Qu, xian Qin, Qiao Chen, Yang Luo*, Wei Wu*. Reactive oxygen species-triggered carbon dots-based biomimetic nanotheranostic agents for atherosclerosis management. Advanced Functional Materials. 2024: 20242405629. (Nature Index, IF: 18.5). DOI: 10.1002/adfm.202405629.

[3] Yi Chen, Hengyi Chen, Xiaohui Chen, Chong Zhang, Chenyu Sun, Zhizeng Wang*, Jichun Yang*, Yang Luo*. Precision Detection of Hepatocellular Carcinoma-Associated Telomerase RNA with SA@Comb-HCR Nanosystem. Biosensors and Bioelectronics. 2024; 261, 116496（IF:10.7）DOI: 10.1016/j.bios.2024.116496.

[4] Zhang, H., X. Hu, X. Bao, W. Tu, Q. Wan, Z. Yu, J. Xie, X. Qiu, W. Gu, Z. Gao, Y. Wang, C. Wang, and Yang Luo*. Commercial Strip-Inspired One-Pot Crispr-Based Chip for Multiplexed Detection of Respiratory Viruses. Small Methods. 2024: e2400917. (IF:15.367) DOI: 10.1002/smtd.202400917.

[5] Zining Wang, Xiaohui Chen, Xiaopei Qiu, Yi Chen, Tian Wang, Linxi Lv, Xinlin Guo, Fei Yang, Miao Tang, Wei Gu*, and Yang Luo*. High-Fidelity Sensitive Tracing Circulating Tumor Cell Telomerase Activity. Analytical Chemistry. 2024, 96, 14, 5527–5536. (Nature Index, IF: 6.986). DOI:10.1021/acs.analchem.3c05749.

[6] Ying Zhu; Tian Wang; Zining Wang; Xiaohui Chen; Liu Wang; Ruyan Niu; Zixin Sun; Chong Zhang;Yang Luo*; Yijie Hu*, and Wei Gu*. Low shear stress exacerbates atherosclerosis by inducing the generation of neutrophil extracellular traps via Piezo1-mediated mechanosensation. Atherosclerosis. 2024; 391: 117473 (IF:5.3) DOI: 10.1016/j.atherosclerosis.2024.117473.

[7] Zhou, F., L. Pan, X. Ma, J. Ye, Z. Xu, C. Yuan, C. Shi, D. Yang, Yang Luo*, M. Li, and P. Wang. In Situ, Fusion-Free, Multiplexed Detection of Small Extracellular Vesicle miRNAs for Cancer Diagnostics. Analytical Chemistry, 2024: 15665-15673. (Nature Index, IF: 6.986)  DOI:10.1021/acs.analchem.4c03129.

[8] Xudong Bao, Xiaolin Hu, Qiwu Wan, Hong Zhang*, Yang Luo*. Development of Digital Polymerase Chain Reaction Technology and Its Progress in Disease Detection. Chinese Journal of Analytical Chemistry. 2024;52(1):13-21. (IF:1.2) DOI: 10.19756/j.issn.0253-3820.231323.

[9] Zhongbo Yang,Dandan Li,Ligang Chen,Fucheng Qiu,Shihan Yan,Mingjie Tang,Chunlei Wang,Lihua Wang,Yang Luo,Fei Sun,Jiaguang Han,Chunhai Fan,Jiang Li*,Huabin Wang*.Near-Field Terahertz Morphological Reconstruction Nanoscopy for Subsurface Imaging of Protein Layers. ACS Nano. 2024;18, 14, 10104–10112 (Nature Index, IF: 17.10). DOI: 10.1021/acsnano.3c12776.

2023年

[1] Beibei Fu, Yan Xiong, Zhou Sha, Weiwei Xue, Binbin Xu, Shun Tan, Dong Guo, Feng Lin, Lulu Wang, Jianjian Ji, Yang Luo*, Xiaoyuan Lin*, Haibo Wu*. SEPTIN2 suppresses an IFN-γ-independent, proinflammatory macrophage activation pathway. Nature Communications. 2023; 14(1):7441. (Nature Index, IF:16.6). DOI: 10.1038/s41467-023-43283-2.

[2] Jichun Yang*, Chong Zhang, Xiaohui Chen, Daijun Zhou, Zixin Sun, Ruyan Niu, Ying Zhu, Hengyi Chen, Liu Wang, Yi Chen, Yuhan Wang, Yunqian Fu, Ningyu Ma, Jianjun Li*, Yang Luo*. Ultra-efficient radio-immunotherapy for reprogramming the hypoxic and immunosuppressive tumor microenvironment with durable innate immune memory. Biomaterials. 2023; 302:122303. (IF:14.0). DOI: 10.1016/j.biomaterials.2023.122303.

[3] Chenxi Ju, Mingxia Zhou, Dan Du, Chang Wang, Jieqiong Yao, Hongle Li, Yang Luo*, Fucheng He*, Jing He*. EIF4A3-mediated circ_0042881 activates the RAS pathway via miR-217/SOS1 axis to facilitate breast cancer progression. Cell Death & Disease. 2023; 14(8):559. (IF:9.0). DOI: 10.1038/s41419-023-06085-4.

[4] Ruyan Niu, Xiaohui Chen, Zixin Sun, Liu Wang, Zining Wang, Chong Zhang, Dan Ding, Jichun Yang*, Yongzhong Wang*, Yang Luo*. A smart TESTER for reliable discrimination of cancer-derived small extracellular vesicles. Analytica Chimica Acta. 2023; 1276:341636. (IF:6.2). DOI: 10.1016/j.aca.2023.341636

[5] Zhigang Liu, Jiahui Liang, Hangzhan Hu, Mengli Wu, Jingjing Ma, Ziwei Ma, Jianing Ji, Hengyi Chen, Xiaoquan Li, Zhizeng Wang, Yang Luo*. Development of an Effective Neutralizing Antibody Assay for SARS-CoV-2 Diagnosis. International Journal of Nanomedicine. 2023;18:3125-3139. (IF:8.0). DOI: 10.2147/IJN.S408921.

[6] Heng Li, Qizhao Huang, Hong Zhang, Zhenxing Liu, Xiaohui Chen, Lilin Ye, Yang Luo*. The land-scape of immune response to monkeypox virus. EBioMedicine. 2023; 87: 104424. (IF:11.2). DOI: 10.1016/j.ebiom.2022.104424.

[7] Liu Wang, Kang Wang, Xiaohui Wang, Ruyan Niu, Xiaohui Chen, Ying Zhu, Zixin Sun, Jichun Yang*, Guoxiang Liu*, Yang Luo*. Intelligent dual-lock deoxyribonucleic acid automatons boosting precise tumor Imaging. ACS Applied Materials & Interfaces. 2023; 15(3): 3826-3838. (IF:10.383). DOI: 10.1021/acsami.2c20024.

[8] Zixin Sun, Xiaohui Chen, Ruyan Niu, Hengyi Chen, Ying Zhu, Chong Zhang, Liu Wang, Huaming Mou*,Hong Zhang*, Yang Luo*. Liposome fusogenic enzyme-free circuit enables high-fidelity determination of single exosomal RNA. Materials Today Bio. 2023; 19: 100613. (IF:10.761). DOI: 10.1016/j.mtbio.2023.100613.

[9] Qi Zhao, Guangchao Qing, Jie Yu, Ying Liu, Jianliang Shen, Yang Luo*, Xingjie Zan*, Shengliang Li*. De novo design of highly efficient type-I photosensitizer based on π-conjugated oligomer for photodynamic eradication of multidrug-resistant bacterial infections. Chinese Chemical Letters. (IF:8.46). DOI:10.1016/j.cclet.2023.108535.

[10] Hengyi Chen, Xiaohui Chen, Yi Chen, Chong Zhang, Zixin Sun, Jiaxi Mo, Yongzhong Wang, Jichun Yang, Dongsheng Zou, Yang Luo*. High-fidelity imaging of intracellular microRNA via a bioorthogonal nanoprobe.Analyst.2023;148(8):1682-1693. (IF:5.227). DOI: 10.1039/d3an00088e.

[11] Haixia Liu, Xiaohui Chen, Yimin Jia, Hengyi Chen, Xiaohui Wang, Guoxiang Liu*, Yang Luo*. Facing inevitable PARPis resistance: Mechanisms and therapeutic strategies for breast cancer treatment. InterdisciplinaryMedicine.2023;1(2): e20220013. DOI: 10.1002/INMD.20220013

2022年

[1] Xiaohui Chen, Yun Deng, Ruyan Niu, Zixin Sun, Batool Alya, Liu Wang, Chong Zhang, Ningyu Ma, Qingtang Yang, Guoxiang Liu*, Jichun Yang*, Yang Luo*. Cancer-derived small extracellular vesicles PICKER. Analytical Chemistry. 2022; 94(38): 13019-13027. (Nature Index, IF: 8.008). DOI: 10.1021/acs.analchem.2c01683. Featured as Front Cover

[2] Xingle Yu, Xiaohui Chen, Zixin Sun, Ruyan Niu, Yun Deng, Liu Wang, Ying Zhu, Liangliang Zhang, Hong Zhang, Kang Wang, Jichun Yang, Wei Gu*, Guoxiang Liu*, and Yang Luo*. Ultracentrifugation-free enrichment and quantification of small extracellular vesicles. Analytical Chemistry. 2022; 94(29): 10337-10345. (Nature Index, IF: 8.008). DOI: 10.1021/acs.analchem.1c05491.

[3] Xiaolin Hu, Weichao Qin, Rui Yuan, Liangliang Zhang, Liangting Wang, Ke Ding, Ruining Liu, Wanyun Huang, Hong Zhang*, Yang Luo*. Programmable molecular circuit discriminates multidrug-resistant bacteria. Materials Today Bio. 2022; 16: 100379. (IF: 10.761). DOI: 10.1016/J.MTBIO.

[4] Yuan Rui, Bai Xiaopeng, Hu Xiaolin, Zhang Hong, Hou Changjun*, Long Quanxin*,Yang Luo*. CATCH: high specific transcriptome-focused fusion gene variants discrimination. Chemical Communications. 2022; 58(55): 7618-7621. (Nature Index, IF: 6.065). DOI: 10.1039/D2CC02660K. Featured as Front Cover

[5] Heng Li, Hong Zhang, Ke Ding, Xiaohui Wang, Guiyin Sun, Zhenxing Liu*, Yang Luo*. The evolving epidemiology of monkeypox virus. Cytokine Growth Factor Reviews. 2022; 68: 1-12. (IF:17.6). DOI: 10.1016/j.cytogfr.2022.10.002.

[6] Liangliang Zhang, Xianxian Zhao, Xiaolin Hu, Yi Zhang, Ruining Liu, Hai Peng, Hong Zhang*, Yang Luo*. Probing low abundant DNA methylation by CRISPR-Cas12a-assisted cascade exponential Amplification. Analyst. 2022; 147(12): 2655-2661. (IF: 4.616). DOI: 10.1039/D2AN00170E. Featured as Back Cover

2021年

[1] Hong Zhang, Ruining Liu, Qingmei Li, Xiaolin Hu, Lixiang Wu, Ye Zhou, Guangchao Qing, Rui Yuan, Junjie Huang, Wei Gu, Yanyao Ye, Chao Qi, Mei Han, Xiaohui Chen, Xun Zhu, Yun Deng, Liangliang Zhang, Hengyi Chen, Haoran Zhang, Weiyin Gao, Yao Liu, Yang Luo*. Flipped quick-response code enables reliable blood grouping. ACS Nano. 2021; 15(4): 7649-7658. (Nature Index, IF: 14.588). DOI: 10.1021/acsnano.1c01215.

[2] Rui Yuan, Wanyan Tang, Hong Zhang, Wenxin You, Xiaolin Hu, Haiwei Zhang, Ling Chen, Weiqi Nian*, Shijia Ding*, and Yang Luo*. Palindromic-assisted self-annealing transcription amplification for reliable genotyping of epidermal growth factor receptor exon mutations. Biosensors & Bioelectronics. 2021; 194: 11363. (IF: 10.618). DOI: 10.1016/J.BIOS.2021.113633.

[3] Jing Bao, Xiaopei Qiu, Deqiang Wang, Huisi Yang, Jiaying Zhao, Yanli Qi, Liangliang Zhang, Xiaohui Chen, Mei Yang, Wei Gu, Danqun Huo*, Yang Luo*, Changjun Hou*. Carbon nanomaze for biomolecular detection with zeptomolar sensitivity. Advanced Functional Materials . 2021; 31(14). (Nature Index, IF: 16.836). DOI: 10.1002/adfm.202006521. Featured as Back Cover

[4] Yingshu Guo, Di Wu, Xu Zhang, Kaixiang Zhang, Yang Luo*.Biomolecules on cell-derived extracellular vesicles chariots as warriors to repair damaged tissues. Nanoscale. 2021; 13(38): 16017-16033. (IF: 7.79). DOI: 10.1039/D1NR04999B.

2020年

[1] Jianxiong Xu, Jinxuan Wang, Juhui Qiu*, Hua Liu, Yi Wang, Yuliang Cui, Rose Humphry, Nan Wang, Colm DurKan, Yaokai Chen, Yanqiu Lu, Qinfeng Ma, Wei Wu, Yang Luo, Lehui Xiao*, Guixue Wang*. Nanoparticles retard immune cells recruitment in vivo by inhibiting chemokine expression. Biomaterials. 2021; 265: 120392.(IF: 10.317). DOI: 10.1016/j.biomaterials.2020.120392.

[2] Xiaohui Chen, Mei Jia, Lianhua Liu, Xiaopei Qiu, Hong Zhang, Xingle Yu, Wei Gu, Guangchao Qing, Qingmei Li, Xiaolin Hu, Ruixuan Wang, Xianxian Zhao, Liangliang Zhang, Xianfeng Wang, Colm Durkan, Nan Wang, Guixue Wang*, Yang Luo*. High-fidelity determination and tracing of small extracellular vesicle cargoes. Small. 2020; 16(40): e2002800.(IF: 11.459). DOI:10.1002/smll. 202002800. Featured as Front Cover

[3] Jing Bao, Xiaopei Qiu, Huisi Yang, Wenqiang Lu, Mei Yang, Wei Gu, Lixiang Wu, Danqun Huo*, Yang Luo*, Changjun Hou*. Disposable 3D GNAs/AuNPs DNA-circuit strip for miRNAs dynamic quantification. Small. 2020; 16(39): e2001416. (IF: 11.459). DOI:10.1002/smll.202001416.

[4] Xianxian Zhao, Liangliang Zhang, Weiying Gao, Xingle Yu, Wei Gu, Weiling Fu*, Yang Luo*. Spatiotemporally controllable microRNA imaging in living cells via NIR-activated nanoprobe. ACS Applied Materials & Interfaces. 2020; 12(32): 35958-35966. (IF: 8.758). DOI:10.1021/acsami.0c10962.

[5] Juhui Qiu, Jianxiong Xu, Kang Zhang, Wei Gu, Liming Nie, Guixue Wang*, Yang Luo*. Refining cancer management using integrated liquid biopsy. Theranostics. 2020; 10(5): 2374-84. (IF: 8.579). DOI: 10.7150/thno.40677. Featured as Front Cover

[6] Xianxian Zhao, LeiliZeng, QiangMei, Yang Luo*. Allosteric probe-initiated wash-free method for sensitive extracellular vesicle detection through dual cycle-assisted CRISPR-Cas12a. ACS Sensors. 2020; 5(7): 2239-2246 (IF: 7.333). DOI: 10.1021/acssensors.0c00944.

[7] Xianfeng Wang, Xiaolong Chen, Chengxiang Chu, Yuanyi Deng, Mei Yang, Zhong Ji, Faliang Xu, Danqun Huo*, Yang Luo*, Changjun Hou*. Four-stage signal amplification for trace ATP detection using allosteric probe-conjugated strand displacement and CRISPR/Cpf1 trans-cleavage (ASD-Cpf1). Sensors and Actuators: B. Chemical. 2020; 323: 128653 (IF: 7.1). DOI: 10.1016/j.snb.2020.128653.

[8] Xianxian Zhao, Canjun Luo, Qiang Mei, Hongmin Zhang, Wenqing Zhang, Dongwei Su*, Weiling Fu*, Yang Luo*. Aptamer-cholesterol-mediated proximity ligation assay for accurate Iodentification of exosomes. Analytical Chemistry. 2020; 92(7): 5411-5418 (Nature Index, IF: 6.350). DOI: 10.1021/acs.analchem.0c00141. ESI高被引

[9] Ruixuan Wang, Xianxian Zhao, Xiaohui Chen, Xiaopei Qiu, Guangchao Qing, Hong Zhang, Liangliang Zhang, Xiaolin Hu, Zhuoqi He, Daidi Zhong, Ying Wang, Yang Luo*. Rolling circular amplification (RCA)-assisted CRISPR/Cas9 cleavage (RACE) for highly specific detection of multiple extracellular vesicle microRNAs. Analytical Chemistry. 2020; 92(2): 2176-2185. (Nature Index, IF: 6.350). DOI: 10.1021/acs.analchem.9b04814. ESI高被引

[10] Xianxian Zhao, Wenqing Zhang, Xiaopei Qiu, Qiang Mei, Yang Luo*, Weiling Fu*. Rapid and sensitive exosomes detection with CRISPR/Cas12a. Analytical and BioAnalytical Chemistry. 2020; 412(3): 601-9 (IF: 3.286). DOI: 10.1007/s00216-019-02211-4. ESI高被引

[11] Guangchao Qing, Hong Zhang, Yang Bai, Yang Luo*. Traditional chinese and western medicines jointly beat COVID-19 pandemic. Chinese Journal of Integrative Medicine. 2020; 26(6): 403-404 (IF: 1.545). DOI:10.1007/s11655-020-3095-6.

2017—2019年

[1] Guangchao Qing, Xianxian Zhao, Ningqiang Gong, Jing Chen, Xianlei Li, Yaling Gan, Yongchao Wang, Zhen Zhang, Yuxuan Zhang, Weisheng Guo*, Yang Luo*, XingJie Liang*.Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection. Nature Communications. 2019; 10(1): 1-12 (Nature Index, IF: 11.878). DOI: 10.1038/s41467-019-12313-3.

[2] Adil Hassan,Ahmad Ud Din,Yuan Zhu,Kun Zhang,Tianhan Li,Yi Wang, Yang Luo*, Guixue Wang*.Updates in understanding the hypocholesterolemia effect of probiotics on atherosclerosis. Applied Microbiology and Biotechnology. 2019; 103(7): 5993-6006 (IF: 3.53). DOI: 10.1007/s00253-019-09927-4.

[3] Guangchao Qing, Ningqiang Gong, Xiaohui Chen, Jing Chen, Hong Zhang, Yongchao Wang, Ruifang Wang, Shouwen Zhang, Zhen Zhang, Xianxian Zhao, Yang Luo*, Xing-Jie Liang*. Natural and engineered bacterial outer membrane vesicles. Biophysics Reports. 2019; 5(4): 184-198. DOI: 10.1007/s41048-019-00095-6

[4] Hong Zhang, Xiaopei Qiu, Yurui Zou, Yanyao Ye,Chao Qi, Lingyun Zou, Xiang Yang, Ke Yang, Yuanfeng Zhu, Yongjun Yang, Yang Zhou, Yang Luo*. A dye-assisted paper-based point-of-care assay for fast and reliable blood grouping. Science Translational Medicine. 2017; 9, eaaf9209. (Nature Index, IF: 16.796). DOI: 10.1126/scitranslmed.aaf9209. Featured as Front Cover

[5] Chuanfen Zheng, Hui Zeng, Hui Lin, Jia Wang, Xiaobin Feng, Zhiqun Qiu, Ji-an Chen, Jiaohua Luo, Yang Luo, Yujing Huang, Lingqiao Wang, Wenyi Liu, Yao Tan, Anwei Xu, Yuan Yao, Weiqun Shu*. Serum microcystin levels positively linked with risk of hepatocellular carcinoma: A case-control study in southwest china. Hepatology. 2017; 66(5): 1519 (IF: 6.91). DOI: 10.1002/hep.29310.

[6] Wenyi Liu, Lingqiao Wang, Xiaohong Yang, Hui Zeng, Renping Zhang, Chaowen Pu, Chuanfen Zheng, Yao Tan, Yang Luo, Xiaobin Feng, Yingqiao Tian, Guosheng Xiao, Jia Wang, Yujing Huang, Jiaohua Luo, Lei Feng, Feng Wang, Changyou Yuan, Yuan Yao, Zhiqun Qiu, Ji-an Chen, Liping Wu, Qingqing Nong, Hui Lin*, Weiqun Shu*. Environmental microcystin exposure increases liverinjury risk induced by hepatitis B virus combined with aflatoxin: A cross-sectional study in southwest china. Environmental Science & Technology. 2017; 51(11): 6367-6378 (IF: 6.58). DOI: 10.1021/acs.est.6b05404.

[7] Fei Chen, Weiyin Gao, Xiaopei Qiu, Hong Zhang, Lianhua Liu, Pu Liao*, Weiling Fu*, Yang Luo*. Graphene quantum dots in biomedical applications: Recent advances and future challenges. Frontiers in Laboratory Medicine. 2017; 1(4): 192-199. (IF: 5.058). DOI: 10.1016/j.flm.2017.12.006.

[8] Yang Luo*, Caiping Song, Hongyan Zhang, Yungui Wang*, Hao Wu*. Toward sustainable and effective control: experience of China Ebola treatment Center in Liberia. Journal of Microbiology Immunology and Infection. 2017; 50(1): 1-3. (IF: 2.955). DOI: 10.1016/j.jmii.2016.04.003.

2014—2016年

[1] Xuefeng Zou, Li Zhang, Zhaojun Wang, Yang Luo*. Mechanisms of the antimicrobial activities of graphene materials. Journal of the American Chemical Society. 2016; 138(7): 2064-2077. (Nature Index, IF: 13.038). DOI: 10.1021/jacs.5b11411. ESI高被引， JACS Spotlights

[2] Xiang Yang, Xiang Zhao, Ke Yang, Yueping Liu, Yu Liu, Weiling Fu*, Yang Luo*. Biomedical applications of terahertz spectroscopy and imaging. Trends in Biotechnology. 2016; 34(10): 810-824. (IF: 12.065). DOI: 10.1016/j.tibtech.2016.04.008. ESI高被引

[3] Hui Lin,Wenyi Liu,Hui Zeng,Chaowen Pu,Renping Zhang,Zhiqun Qiu,Ji-An Chen,Lingqiao Wang,Yao Tan,Chuanfen Zheng,Xiaohong Yang,Yingqiao Tian,Yujing Huang,Jiaohua Luo, Yang Luo*, Xiaobin Feng, Guosheng Xiao, Lei Feng, Heng Li, Feng Wang, Changyou Yuan, Jia Wang, Ziyuan Zhou, Tiantian Wei, Yonglin Zuo, Liping Wu, Lixiong He, Yaoping Guo, Weiqun Shu*. Determination of Environmental Exposure to Microcystin and Aflatoxin as a Risk for Renal Function Based on 5493 Rural People in Southwest China. Environmental Science & Technology. 2016; 50(10): 5346-5356. (IF: 7.864). DOI: 10.1021/acs.est.6b01062.

[4] Xiang Yang, Ke Yang, Yang Luo*, Weiling Fu*. Terahertz spectroscopy for bacterial detection: opportunities and challenges. Applied Microbiology and Biotechnology. 2016; 100(12): 5289-5299. (IF: 3.376). DOI: 10.1007/s00253-016-7569-6.

[5] Xiaopei Qiu, Hong Zhang, Helian Yu, Tianlun Jiang, Yang Luo*. Duplex-specific nuclease-mediated bioanalysis. Trends in Biotechnology. 2015; 33(3): 180-188. (IF: 11.958). DOI: 10.1016/j.tibtech.2014.12.008.

[6] Xiaopei Qiu, Xing Liu, Wei Zhang, Hong Zhang, Tianlun Jiang, Dongli Fan, Yang Luo*. Dynamic Monitoring of MicroRNA–DNA Hybridization Using DNAase-Triggered Signal Amplification. Analytical Chemistry. 2015; 87(12): 6303-6310. (Nature Index, IF: 6.350). DOI: 10.1021/acs.analchem.5b01159.

[7] Yang Luo*, Chaoming Wang, Tianlun Jiang, Bo Zhang, Junfu Huang, Pu Liao, Weiling Fu*. Interference-free determination of ischemia-modified albumin using quantum dot coupled X-ray fluorescence spectroscopy. Biosensors and Bioelectronics. 2014; 51: 136-142. (IF: 7.476). DOI: 10.1016/j.bios.2013.07.046.

[8] Liqun Zhang, Yunxia Wang, Ming Chen, Yang Luo, Kun Deng, Dong Chen, Weiling Fu*. A new system for the amplification of biological signals: RecA and complimentary single strand DNA probes on a leaky surface acoustic wave biosensor. Biosensors and Bioelectronics. 2014; 60(60): 259-264. (IF: 7.476). DOI: 10.1016/j.bios.2014.04.037.

[9] Yuan Yao, Ying Jiang, Mei Han, Yu Xia, Yuchen He, Yonghu Wang, Yang Luo, Bo Zhang*. Screening and identification of potential predictive biomarkers for Down' s syndrome from second trimester maternal serum. Expert Review of Proteomics. 2014; 12(1) : 97–107. (IF: 2.896). DOI: 10.1586/14789450.2015.979796.

[10] Xing Liu, Yang Luo*. Surface modifications technology of quantum dots based biosensors and their medical applications. Chinese Journal of Analytical Chemistry. 2014; 42(7): 1061-1069. (IF: 0.554). DOI: 10.1016/S1872-2040(14)60753-2.

[11] Xiaopei Qiu, Hong Zhang, Tianlun Jiang, Yang Luo*. Biological and Medical Applications of Duplex-Specific Nuclease. Progress in Chemistry. 2014; 26(11):1840-1848. (IF: 0.714). DOI: 10.7536/PC140808.

2006—2013年

[1] Yang Luo, Mainul Hossain, Chaoming Wang, Yong Qiao, Jincui An, Liyuan Ma, Ming Su*. Targeted nanoparticles for enhanced X-ray radiation killing of multidrug-resistant bacteria. Nanoscale. 2013; 5(2): 687-694. (IF: 7.79). DOI: 10.1039/c2nr33154c.

[2] Yang Luo*, Xing Liu, Tianlun Jiang, Pu Liao*, Weiling Fu*. Dual-aptamer-based biosensing of toxoplasma antibody. Analytical Chemistry. 2013; 85(17): 8354-8360. (Nature Index, IF: 6.350). DOI: 10.1021/ac401755s.

[3] Yang Luo, Chaoming Wang, Ping Peng, Mainul Hossain, Tianlun Jiang, Weiling Fu, Yi Liao, Ming Su*. Visible light mediated killing of multidrug-resistant bacteria using photoacids. Journal of Materials Chemistry B. 2013; 1(7): 997-1001. (IF: 4.872). DOI: 10.1039/c2tb00317a.

[4] Chaoming Wang, Yan Hong, Minghui Zhang, Mainul Hossain, Yang Luo, Ming Su*. Thermal fingerprint of silica encapsulated phase change nanoparticles. Nanoscale. 2012; 4(10): 3237-3241. (IF: 5.914). DOI: 10.1039/c2nr30092c.

[5] Yang Luo, Chaoming Wang, Mainul Hossain, Yong Qiao, Liyuan Ma, Jincui An, Ming Su*. Three-dimensional microtissue assay for high-throughput cytotoxicity of nanoparticles. Analytical Chemistry. 2012; 84(15): 6731-6738. (Nature Index, IF: 5.856). DOI: 10.1021/ac301191j.

[6] Mainul Hossain, Yang Luo(equal contribution), Zhaoyong Sun, Chaoming Wang, Minghui Zhang, Hanyu Fu, Yong Qiao, Ming Su*. X-ray enabled detection and eradication of circulating tumor cells with nanoparticles. Biosensors and Bioelectronics. 2012; 38(1): 348-354. (IF: 5.602). DOI: 10.1016/j.bios.2012.06.020.

[7] Yang Luo, Mainul Hossain, Chaoming Wang, Yong Qiao, Liyuan Ma, Ming Su*. On-chip radiation biodosimetry with three-dimensional microtissues. Analyst. 2012; 137(15): 3441-3444. (IF: 4.033). DOI: 10.1039/c2an35046g.

[8] Yang Luo, Bo Zhang, Ming Chen, Tianlun Jiang, Daiyang Zhou, Junfu Huang, Weiling Fu*. Sensitive and rapid quantification of C-reactive protein using quantum dot-labeled microplate immunoassay. Journal of Translational Medicine. 2012; 10(1): 24. (IF: 3.694). DOI: 10.1186/1479-5876-10-24.

[9] Yang Luo, Chaoming Wang, Yong Qiao, Mainul Hossain, Liyuan Ma, Ming Su*. In vitro cytotoxicity of surface modified bismuth nanoparticles. Journal of Materials Science: Materials in Medicine. 2012; 23(10): 2563-2573. (IF: 2.272). DOI: 10.1007/s10856-012-4716-1.

[10] Yang Luo*, Bo Zhang, Ming Chen, Jue Wang, Xue Zhang, WeiYin Gao, JunFu Huang, Weiling Fu*. Rapid and simultaneous determination of essential minerals and trace elements in human milk by improved flame atomic absorption spectroscopy (FAAS) with microwave digestion. Journal of Agricultural and Food Chemistry. 2010; 58(17): 9396-9400. (IF: 2.857). DOI: 10.1021/jf100940e.

[11] Yang Luo, Ming Chen, Qianjun Wen, Meng Zhao, Bo Zhang, Xiaoyan Li, Feng Wang, Qing Huang, Chunyan Yao, Tianlun Jiang*. Rapid and simultaneous quantification of 4 urinary proteins by piezoelectric quartz crystal microbalance immunosensor array. Clinical Chemistry. 2006; 52(12): 2273-2280. (IF: 7.717). DOI: 10.1373/clinchem.2006.073569.

[1]Automatic test card for multi-blood group system and test method，PCT/CN2021/078825（美国、澳大利亚、南非授权）

[2]一种用于凝血酶原时间检测的便携式装置，202410377766.5

[3]一种纳米激动剂及其制备方法和应用，202310829700.0

[4]一种基于荧光探针的用于输血前检测的结构及应用，202410321950.8

[5]一种靶向肝癌的纳米颗粒的制备方法和应用，202311250866.3

[6]一种基于可变DNA纳米探针的细胞外囊泡检测方法，202310955057.6

[7]一种基于微流控的微型离心装置及应用，202310595780.8

[8]一种DNA纳米探针MB及其应用，202310093797.3

[9]一种基于CRISPR/Cas12a的多核苷酸激酶活性检测方法，202310107943.3

[10]酿酒酵母的特异性探针、定量检测方法及应用，202210768659.6

[11]一种外泌体分离富集方法及其应用，202210724044.3

[12]端粒酶表达丰度和活性综合检测技术的探针组合及其应用，202210692847.5

[13]一种检测融合基因及其变体的系统以及方法和应用，202210611063.5

[14]多重耐药微生物的检测方法，202110614183.6

[15]胞外囊泡富集检测方法，202110614317.4

[16]DNA甲基化的超敏检测方法及其应用，202110615426.8

[17]一种用于双位点顺反式突变检测的引物、探针组合物及其应用，202111162072.2

[18]一种检测RNA病毒核酸的高通量数字PCR试剂盒及检测方法，202010307516.6

[19]一种仿生类细胞结构传感器及其制备方法和应用，202011054573.4

[20]一种多血型系统自动检测卡及检测方法，202010143305.3

[21]多种病原菌平行检测的滚环扩增-太赫兹超材料生物传感器及其检测方法，201610061139.6

[22]滚环扩增-太赫兹超材料生物传感器及快速检测多重耐药结核杆菌的方法，201610060880.0

[23]Pathogenic microorganism nucleic acid non-amplification detection and classification method，1501381.5（英国）

[24]一种便携式血型系统检测试纸及其检测方法，201510106833.0

[25]一种高通量血型系统检测装置及方法，201510106835.X

[26]Pathogenic microorganism nucleic acid non-amplification detection and classification method，14/423,638（美国）

[27]Pathogenic microorganism nucleic acid non-amplification detection and classification method，2013307981（澳大利亚）

[28]缺血性心脏病检测试剂盒及其应用，201310286843.8

[29]病原微生物核酸无扩增检测与分型方法，201210326601.2

[30]多功能磁性荧光微球及其制备方法和应用，201210123475.0

[31]肠出血性大肠杆菌O157:H7多色量子点快速检测试剂盒及其检测方法，201010264295.5

[32]多色量子点组合微球编码的液体芯片及其制备方法和检测方法，200910191281.2

[33]量子点组合微球标记核酸探针及其制备方法和应用，200910103354.8

[34]量子点标记核酸探针及其制备方法和应用，200910103353.3

[35]基于量子点的核酸传感器及其制备方法和检测方法，200910103211.7

[36]多靶标量子点标记核酸芯片及其制备方法和检测方法，200910103210.2

国家级项目

[1]癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项，重大慢病诊疗关键检验项目医学决定水平的建立与应用研究（临床研究）（2025ZD0551300），项目负责人，2025-2029

[2]国家杰出青年科学基金，重大疾病生物标志物精准检测研究（82125022），项目负责人，2022-2026

[3]国家自然科学基金重点专项，脓毒症的早期识别、危险分层和精准治疗的多学科交叉技术创新与转化研究（82241059），课题负责人，2023-2025

[4]科技部国家重点研发计划课题，癌症临床实验室检验新技术与参考系统研究（2022YFC2009603），课题负责人，2022-2025

[5]中央军委科技委基础加强计划（JG2023012），项目负责人，2022-2024

[6]国家自然科学基金面上项目，CRISPR分子逻辑门探针的构筑及其用于EGFR多点突变时空分辨的研究（82072383），项目负责人，2021-2024

[7]国家自然科学基金面上项目，DNA四面体纳米探针介导的胞外囊泡内microRNA原位多重检测技术研究（81871733），项目负责人，2019-2022

[8]国家自然科学基金面上项目，DSN酶介导的胰腺癌早期诊断多联cmiRNA标志物直接检测的实验研究（81572079），项目负责人，2016-2019

[9]国家自然科学基金面上项目，基于量子点LBL-SA的荧光信号级联放大技术直接检测多重耐药MTD的实验研究（81371899），项目负责人，2014-2017

[10]国家自然科学基金青年科学基金项目，高分辨检测复杂染色体畸变的量子点多色荧光探针的研究（30900348），项目负责人，2010-2012

省部级及其他项目

[1]高致病性病原微生物重庆市重点实验室2025年开放基金，病原微生物即时超敏检测技术与试剂的研发与评估（2025ZDSYSZD002），项目负责人，2025-2026

[2]重庆市科卫联合中医药科研重点项目，基于姜黄外泌体的可吸入式肺癌疫苗研究（2025ZD0551300），项目负责人，2025-2026

[3]云南省重点科技专项，基于跨模态的早期肺癌智慧预警与诊断系统研发（202302AA310039），项目负责人，2023-2025

[4]中央高校基本科研业务费项目前沿交叉专项，老年性疾病智慧监测及预警标尺构建策略研究（2022CDJQY-002），项目负责人，2022-2025

[5]四川省科技计划重点项目，基于病原学“多发触点”的重大传染病研判关键技术及流行预警模型的研究（2022YFS0052），项目负责人，2022—2023

[6]留学人员回国创业创新支持计划，携CRISPR元件的类囊泡用于肿瘤EVs标志物原位多重检测研究（CX2021010），项目负责人，2022-01--2022-12

[7]四川省科技计划重点项目，重大传染病防控及新型疫苗构建的关键技术研究（2021YFQ0060），项目负责人，2021-2023

[8]重庆市自然科学基金重点项目，整合CRISPR元件的工程化类细胞诱捕病毒核酸原位超敏检测研究（CSTC2020JCYJ-ZDXM0111），项目负责人，2020-2022

[9]教育部首批高校新冠肺炎防治科技攻关重点项目，新冠病毒POCT快速检测试剂（微流控化学发光）研发，项目负责人，2020

[10]重庆市杰出青年基金，基于荧光磁性纳米自组装的核酸直接检测关键技术研究（CSTC2014JCYJJQ10007），项目负责人，2014-2018

[11]重庆市自然科学基金重点项目，基于BSA-LBL荧光信号级联放大的HBV核酸直接检测与分型（CSTC2013JJB10012），项目负责人，2013-2016

[1]全球卓越工程师大赛金奖，2025

[2]重庆市“渝创星火”科技成果转化大赛一等奖，2025

[3]重庆市科技进步一等奖，2023，排名第1

[4]中华医学科技奖青年科技奖，2023，排名第1

[5]重庆市技术发明一等奖，2019，排名第1

[6]中国发明协会创新创业成果一等奖，2022，排名第1

[7]中国商业联合会科技进步一等奖，2025，排名第1

[8]重庆市科技进步一等奖，2022，排名第3

[9]入选全球前2%顶尖科学家榜单，2023

[10]国家科技进步二等奖，2010，排名第5

[11]“兴渝杯”国际创新创业项目大赛总决赛冠军，2023

[12]重庆市高层次人才创新创业金秋路演总决赛一等奖，2023

[13]沙坪坝区科普工作成绩突出个人，2022

[14]AACC Academy Distinguished Abstract Award，2022

[15]AACC Critical and Point of Care Division Best Abstract Award，2021

[16]AACC Hematology and Coagulation Division’s Best Abstract Award，2021

[17]“英雄杯”中国实验医学杰出青年奖，2021

[18]重庆市最美科技工作者，2020

[19]重庆市最美退役军人，2020

[20]首届全国退役军人创业创新大赛一等奖，2020

[21]重庆市“产学研创新成果奖”一等奖，2019，排名第1

[22]重庆市科协优秀学术论文，2018

[23]AACC International Travel Grant，American Association for Clinical Chemistry，2015

[24]埃博拉出血热疫情防控先进集体荣誉称号（国家人社局\卫健委），2015

[25]CCTV“感动中国”特别人物致敬，2014

[26]AACC Distinguished Abstract Award，American Association for Clinical Chemistry，2014

[27]AACC Student Travel Grant，American Association for Clinical Chemistry，2014

[28]重庆市青年五四奖章，2014

[29]中华预防医学科学技术奖一等奖，2011，排名第5

[30]“十一五”军队医学科技重大成果奖，2010，排名第5

[31]中华医学科学技术奖二等奖，2009，排名第5

[32]重庆市优秀博士学位论文，2009

[1]全国基础医学创新实验总决赛金奖，2025

[2]江苏省研究生生物安全技术与促进创新实践大赛特等奖、一等奖、二等奖，2025

[3]全国基础医学创新实验总决赛银奖，2024

[4]江苏省研究生生物安全技术与促进创新实践大赛一等奖、二等奖、最佳团队奖，2024

[5]江苏省研究生生物安全技术与促进创新实践大赛研究设计组二等奖、生物检验尖端技能组三等奖、最佳团队奖，2023

[6]第八届全国大学生生物医学工程创新设计竞赛三等奖，2023

[7]罗氏大学研究基金三等奖及入围奖，2023

[8]江苏省研究生生物检验科研创新实践大赛创新设计赛道特等奖、一等奖、二等奖，成果汇报赛道二等奖，2022

[9]第八届“互联网+”大学生创新创业大赛，重庆大学金奖，2022

[10]第七届中国国际“互联网+”大学生创新创业大赛，重庆市金奖，2021

[11]第十七届“挑战杯”全国大学生课外学术科技作品竞赛，重庆市特等奖，2021

[12]江苏省研究生生物检验科研创新实践大赛暨首届“泽众杯”医学检验技术技能大赛，成果汇报赛道特等奖、一等奖，创新设计赛道一等奖、二等奖，2021

[13]第六届中国国际“互联网+”大学生创新创业大赛，重庆市金奖，2020

[14]第十届全国大学生电子商务“创新、创意及创业”挑战赛，重庆市二等奖，2020

[15]第二届重庆市两江新区创业创新大赛，最具潜力奖，2020

本课题组热忱欢迎有志于疾病检测新技术开发、诊疗一体化研究、核酸检测等方面研究，具有扎实化学、材料学或医学、细胞生物学、分子生物学、医学检验等知识背景，良好英语能力和较强的实验动手技能的学生报考博士、硕士研究生。

同时热烈欢迎具有基础医学、检验医学、临床医学、细胞生物学、分子生物学、材料学背景的博士加入本课题组工作或做博士后或者弘深青年教师研究。