蔡文立

学历:博士研究生

职称:教授

职务:附属肿瘤医院医学人工智能实验室主任,智能肿瘤学创新研究中心常务副主任,首席AI科学家

邮箱:wenli.cai@cqu.edu.cn

研究方向:智能肿瘤学

学术任职


   Intelligent Oncology执行主编

中国抗癌协会肿瘤人工智能专委会常务委员

中国抗癌协会整合肿瘤相关结节专委会常务委员

 

学习经历

1. 1997-2000年 德国达姆施塔特工业大学弗劳恩霍夫图形研究所,医学图像可视化 博士,师从欧洲图形学奠基人Jose Encarnacao教授

2. 1988-1991年 上海科技大学计算机应用 硕士

3. 1984-1988年 浙江大学计算机软件本科 学士

 

工作经历

1. 2024.12-至今 重庆大学附属肿瘤医院 医学人工智能实验室主任、 智能肿瘤学创新研究中心常务副主任、首席AI科学家、教授、博士/博士后导师

2. 2004-2024.12 麻省总医院影像系三维量化影像(3DQI)实验室主任、博士后导师

3. 2001-2004 美国纽约州立大学石溪分校,医学图像处理博士后,师从开创体可视化研究的奠基人Arie Kaufman教授,从事3D虚拟结肠镜和CTA血管量化分析研究和软件开发

4. 1991-1997 浙江大学CAD&CG国家重点实验室,开始医学图像可视化的研究,1994年获得国家自然科学基金资助,1996年与石教英教授合著出版了国内第一本科学可视化著作《科学计算可视化算法和系统》(科学出版社),破格晋升副研究员

 

研究方向、教学课程

 1.医学人工智能与机器学习大模型;

2.医学图像处理、放射组学与病理组学

3.智能肿瘤学

成果

 

一、文章

 

1.Cai W*. DeepSeek AI: Transforming medical AI with cost-efficiency, transparency, and privacy preservation. Intelligent Oncology. 2025;1(2):172-175. doi:10.1016/j.intonc.2025.03.006.

2.Li Z, Lu J, Zhang B, Si J, Zhang H, Zhong Z, He S, Cai W*, Li T. New Model and Public Online Prediction Platform for Risk Stratification of Vocal Cord Leukoplakia. Laryngoscope. 2024 Oct;134(10):4329-4337. doi: 10.1002/lary.31555. Epub 2024 Jun

3.Cai W*. Uncovering Demographic Bias in Natural Language Processing Tools for Radiology. Radiology. 2024 Oct;313(1):e242723. doi: 10.1148/radiol.242723.

4.Chen Y, Feng L, Huang Z, Zou W, Luo G, Dai G, Zhao W, Cai W, Luo M. Comparison of Diatrizoate and Iohexol for Patient Acceptance and Fecal-Tagging Performance in Noncathartic CT Colonography. J Comput Assist Tomogr. 2024 Jan-Feb 01;48(1):55-63. doi: 10.1097/RCT.0000000000001526. Epub 2023 Aug 8.

5.Zhang K, Luo G, Li W, Zhu Y, Pan J, Li X, Liu C, Liang J, Zhan Y, Zheng J, Li S, Cai W*, Hong G*. Automatic Image Segmentation and Grading Diagnosis of Sacroiliitis Associated with AS Using a Deep Convolutional Neural Network on CT Images. J Digit Imaging. 2023 Oct;36(5):2025-2034.

6.Cai, W*.Feasibility and Prospect of Privacy-preserving Large Language Models in Radiology. Radiology. 2023 Oct;309(1):e232335. doi: 10.1148/radiol.232335.

7.Luo G, Liu T, Lu J, Chen X, Yu L, Wu J, Chen DZ, Cai W. Influence of Data Distribution on Federated Learning Performance in Tumor Segmentation. Radiol Artif Intell. 2023 Apr 26;5(3):e220082. doi: 10.1148/ryai.220082.

8.Zhang JW, Chen W, Ly KI, Zhang X, Yan F, Jordan J, Harris G, Plotkin S, Hao P, Cai W*. DINs: Deep Interactive Networks for Neurofibroma Segmentation in Neurofibromatosis Type 1 on Whole-Body MRI. IEEE J Biomed Health Inform. 2022 Feb;26(2):786-797. doi: 10.1109/JBHI.2021.3087735. Epub 2022 Feb 4.

9.Zhang JW, Chen W, Ly KI, Zhang X, Yan F, Jordan J, Harris G, Plotkin S, Hao P, Cai W. DINs: Deep Interactive Networks for Neurofibroma Segmentation in Neurofibromatosis Type 1 on Whole-Body MRI. IEEE J Biomed Health Inform. 2022 Feb;26(2):786-797.

10.Shi Z, Cai W, Feng X, Cai J, Liang Y, Xu J, Zhen J, Liang X. Radiomics Analysis of Gd-EOB-DTPA Enhanced Hepatic MRI for Assessment of Functional Liver Reserve. Acad Radiol. 2022 Feb;29(2):213-218. doi: 10.1016/j.acra.2021.04.019. Epub 2021 Jun 25.

11.Li H, Shen J, Shou J, Han W, Gong L, Xu Y, Chen P, Wang K, Zhang S, Sun C, Zhang J, Niu Z, Pan H, Cai W, Fang Y. Exploring the Interobserver Agreement in Computer-Aided Radiologic Tumor Measurement and Evaluation of Tumor Response. Front Oncol. 2022 Jan 31;11:691638. doi: 10.3389/fonc.2021.691638.

二、专利

1.智能超声波医学影像检查床,蔡文立,浙江昆捷医疗科技有限公司,CN109171805B,2021-08-20,浙江昆捷医疗科技有限公司;

2. Magnetic Resonance Imaging (MRI)Applications of Three Dimensional Quantitative Imaging (3DQI) for Measuring Bony Anatomy of the Shoulder Joints and Other Joints in the Body,Wenli CaiMGH#24168,2016,Massachusetts General Hospital

3. Volumetric analysis software for neurofibromatosis (NF) in MRI images,Wenli CaiMGH#23334,2015,Massachusetts General Hospital

4. Adaptive Density Correction in Computed Tomographic Images,Wenli CaiUS8000550B2,2010,Massachusetts General Hospital

5. Structure-analysis system, method, software arrangement and computer accessible medium for digital cleansing of computed tomography colonography images,Wenli CaiUS9299156B2,2009,Massachusetts General Hospital

6. Lumen Tracking in Computed Tomographic Images,Wenli CaiUS7965880B2,2007,Massachusetts General Hospital

7.软件注册证:三维影像测量分析软件(QTIE-Lab:量化肿瘤影像评估系统,浙械注准20212210243),蔡文立,浙江昆捷医疗科技有限公司,2021.6.11;

8.软件注册证:三维医学影像软件 (3D-CTC :  CT虚拟肠镜,苏械注准:20232210024),蔡文立,常熟寰汇医学影像公司   2023.01.04;

9.3DQI :三维量化影像分析平台 (开源软件) Wenli Cai, 3D Quantitative Imaging Lab, MGH and Harvard Medical School, 2019 – 2024。

三、承担和参与的科学研究项目

[1]重庆市级项目,MDT-Copilot:构建多模态数据量化分析与生成式 AI 创新融合的虚拟 MDT 智能协同平台.项目负责人(2025.1-2029.12)

四、相关奖励与荣誉

[1]在北美放射学年会上多次获奖,包括一等奖(1次,排名第一)、二等奖(1次,排名第一)、三等奖(7次,4个排名第一),Radiographic奖(6次,4个排名第一)。                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        

[2] Radiology的2023年度和2024年度的杰出审稿人编辑表彰奖。