一、文章
1. Xiong S, Yang C, Fu K, Liao X, Ding Y, Zhou K, Zhang L, Teng Y, Wu C, Li Y, Liang H, Li Y. Case report: Curative effect and mechanism of surufatinib combined with toripalimab in the treatment of 1 case of lung large-cell neuroendocrine carcinoma. Front Oncol. 15:1527719. (2025)
2. Zhou K, Yang C, Li Y. Multi-omics in colorectal cancer liver metastasis: applications and research advances. Cancer Biol Med. 22(6):618–38. (2025)
3. Ding Y, Zhou K, Fu K, Liao X, Xiong S, Yang C, Hu M, Liang G, Zeng X, Li Y, Wang D, Li Y. Case Report: Personalized diagnosis and treatment strategies for three cases of cancer of unknown primary based on molecular testing techniques. Front Oncol. 15:1505271. (2025)
4. Xiong S, Wang D, Tang Y, Lu S, Huang L, Wu Z, Lei S, Liang G, Yang D, Li D, Li Y. HIF1α and HIF2α regulate non-small-cell lung cancer dedifferentiation via expression of Sox2 and Oct4 under hypoxic conditions. Gene. 863:147288. (2023)
5. Zhang J, Yang S, Wang J, Xu Y, Zhao H, Lei J, Zhou Y, Chen Y, Wu L, Zhou M, Li Y, Li Y. Integrated LC-MS metabolomics with dual derivatization for quantification of free fatty acids in fecal samples of hepatocellular carcinoma patients. Journal of Lipid Research. 100143. (2021)
6. Shuanglong xiong, Dairong Li, Donglin Wang, Lumi Huang, Guanzhong Liang, Zhijuan Wu, Jianlin Long, Dan Yang, Yan Teng, Shuangyi Lei, Yan Li*. Circular Rna MYLK promotes glycolysis and proliferation of non-small cell lung cancer cells by sponging miR-195-5p and increasing glucose transporter member 3 expression. Cancer management and research, 12:5469-5478. (2020)
7. Yan LI, Luchun LI, Zhijuan WU,Lulu WANG, Yongzhong WU, Dairong LI, Huiwen MA, Jianghe SHAO, Huiqing YU, Donglin WANG. Silencing of ATM expression by siRNA technique contributes to glioma stem cell radiosensitivity in vitro and in vivo. Oncol Rep, 38(1):325-335 (2017)
8. Yan Li, Luchun Li, Bo Li, Zhijuan Wu, Yongzhong Wu, Ying Wang, Fu Jin, Dairong Li, Huiwen Ma, Donglin Wang. Silencing of ataxia-telangiectasia mutated by siRNA enhances the in vitro and in vivo radiosensitivity of glioma. Oncol Rep, 35(6):3303-3312. (2016)
9. Yan LI, Zhong XU, Bo LI, Zhengzheng ZHANG, HongChong LUO, YuanHu WANG, ZhiZhong LU, XiaoLing WU. Epigenetic silencing of miRNA9 is correlated with promoterproximal CpG island hypermethylation in gastric cancer in vitro and in vivo. Int J Oncol, 45: 2576-2586. (2014)
10. Yan Li, Bo Li, Chun-Ping Xiang, Yu Zhang, Yuan-Yuan Li, Xiao-Ling Wu. Characterization of gastric cancer models from different cell lines orthotopically constructed using improved implantation techniques. World Journal of Gastroenterology, 18(2):136-43. (2012)
11. Yan Li, Bo Li, Yu Zhang, Chun-Ping Xiang, Yuan-Yuan Li, Xiao-Ling Wu. Serial observations on orthotopic gastric cancer model constructed using improved implantation technique. World Journal of Gastroenterology, 17(11): 1442-47.( 2011)
二、承担和参与的科学研究项目
[1]重庆市科委基础科学与前沿研究技术专项重点项目,调控具有P53基因表型差异的GSCs中的自噬对放疗敏感谢性的影响(cstc2015jcyjBX0060);项目负责人(2015.12-2018.12)
[2]重庆市博士后特别资助项目, P53基因表型差异通过调控自噬功能改变GSCs放疗敏感性(Xm2015086),(2015.12-2017.12)
[3]重庆市科委基础科学与前沿研究技术专项一般项目, IDH1突变介导代谢重编程表观调控ATM改变自噬影响胶质瘤放疗敏感性(cstc2018jcyjAX0185),项目负责人(2018.8.1-2021.7.30)
[4]重庆市科卫联合医学项目(中青年高端人才项目),依维莫司联合EP方案一线治疗晚期肺大细胞神经内分泌癌的临床试验研究(2020GDRC005),项目负责人(2020.9.1-2023.8.31)
[5]希思科(CSCO)和黄医药肿瘤研究基金-面上项目,索凡替尼联合特瑞普利二线治疗晚期肺大细胞神经内分泌癌的临床试验研究(Y-HH202102-0200),项目负责人(2023.6.1-2026.6.30)
[6]重庆市自然科学基金面上项目, PPAR-α调控SCD1 介导脂代谢重编程导致结肠癌5-FU 耐药和机制研究(CSTB2024NSCQ-MSX0478),项目负责人(2024.7.1-2027.6.30)
[7]北京康曌基金会面上项目,阿美替尼联合PP化疗和贝伐珠单抗一线治疗EGFR-TP53共突变晚期NSCLC的前瞻性、随机对照、多中心的临床研究(ZLKY-HS25007-1), 项目负责人(2025.8- 2028.8)
[8]重庆市科委基础科学与前沿研究技术专项重点项目, CCN1对结肠癌循环肿瘤细胞失巢凋亡的影响及机制(cstc2015jcyjB0646),项目研究骨干(排名第三)
[9]重庆市科委基础科学与前沿研究技术专项一般项目, p53突变介导miR-34a调控PD-L1表达影响GSCs免疫功能研究(cstc2018jcyjAX0031),项目研究骨干(排名第二)
[10]科研机构绩效激励引导专项, HIFs经逆转录分子网络调控肺癌细胞缺氧逆分化分子机制研究(cstc2018jxjl0249),项目研究骨干(排名第二)
[11]重庆市科委基础科学与前沿研究技术专项一般项目, EGFR/HER2通过IL-6/JAK/STAT3通路影响胃癌中PD-L1表达的研究(cstc2018jcyjAX00814),项目研究骨干(排名第二)
三、专利
1.唐颖,李咏生,李艳,吴志鹃,熊双龙。一种肿瘤切除器。国家发明专利。专利号:CN202011376949.3.
2.唐颖,李咏生,李艳,吴志鹃,熊双龙。一种缓解疼痛用按摩装置。专利号:CN202011407159.7.
四、相关奖励与荣誉
[1] 2017年<重庆医学>中青年医师精准诊疗思路论坛暨第三届“普来乐杯”肺癌病例演讲比赛优秀奖