一、文章
1. Xiaoyu Liu, Weiqin Yang, Alfred Sze-Lok Cheng*. Towards biomarker-driven cancer immunotherapy: the rising of a protein phosphatase regulator. Signal Transduct Target Ther. 2025 ;10(1):340. doi: 10.1038/s41392-025-02425-2.
2. Xiaoyu Liu, Man Liu, Haoran Wu, Wenshu Tang, Weiqin Yang, Thomas T.H. Chan, Lingyun Zhang, Shufen Chen, Zhewen Xiong, Jianxin Liang, Willis Wai-Yiu Si-Tou, Ting Shu, Jingqing Li, Jianquan Cao, Chengpeng Zhong, Hanyong Sun, Tsz Tung Kwong, Howard H.W. Leung, John Wong, Paul Bo-San Lai, Ka-Fai To, Tingxiu Xiang, Joseph Jao-Yiu Sung, Stephen Lam Chan, Jingying Zhou*, Alfred Sze-Lok Cheng*.PPP1R15A-expressing monocytic MDSCs promote immunosuppressive liver microenvironment in fibrosis-associated hepatocellular carcinoma, JHEP Rep. 2024; 6(7):101087. doi: 10.1016/j.jhepr.2024.101087.
3. Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-yiu Sung, Leaf Huang, Rihe Liu, and Alfred Sze-lok Cheng*. Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma. Mol Ther. 2023;31(1):119-133. doi: 10.1016/j.ymthe.2022.09.012.
4. Rui Wu*, Yan Liu, Ruyu Yan, Xiaoyu Liu*, Liang Duan*. Assessment of EN-RAGE, sRAGE and EN-RAGE/sRAGE as potential biomarkers in patients with autoimmune hepatitis. J Transl Med. 2020;18(1):384. doi: 10.1186/s12967-020-02556-w.
5. Man Liu, Jingying Zhou, Xiaoyu Liu, Yu Feng, Weiqin Yang, Feng Wu, Otto Ka-Wing Cheung, Hanyong Sun, Xuezhen Zeng, Wenshu Tang, Myth T S Mok, John Wong, Phillip Chun Yeung, Paul Bo-San Lai, Zhiwei Chen, Hongchuan Jin, Jie Chen, Stephen Lam Chan, Anthony W H Chan, Ka-Fai To, Joseph Jao-Yiu Sung, Minhu Chen, Alfred Sze-Lok Cheng*. Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma. Gut. 2020;69(2):365-379. doi: 10.1136/gutjnl-2018-317257.
6. Tsz Tung Kwong, Zhewen Xiong, Yiling Zhang, Haoran Wu, Jianquan Cao, Patrick P C Wong, Xiaoyu Liu, Jing Wang, Chi Hang Wong, Gary Man-Kit Tse, Joseph Jao-Yiu Sung, Jingying Zhou, Alfred Sze-Lok Cheng*, Stephen Lam Chan*. Overcoming immunotherapy resistance in hepatocellular carcinoma by targeting myeloid IL-8/CXCR2 signaling. Mol Ther. 2025;33(4):1659-1673. doi: 10.1016/j.ymthe.2025.02.002.
7. Wenshu Tang, Jingying Zhou, Weiqin Yang, Yu Feng, Haoran Wu, Myth T S Mok, Lingyun Zhang, Zhixian Liang, Xiaoyu Liu, Zhewen Xiong, Xuezhen Zeng, Jing Wang, Jiahuan Lu, Jingqing Li, Hanyong Sun, Xiaoyu Tian, Phillip Chun Yeung, Yong Hou, Hueng Man Lee, Candice C H Lam, Howard H W Leung, Anthony W H Chan, Ka-Fai To, John Wong, Paul Bo-San Lai, Kelvin K C Ng, Simon K H Wong, Vincent W S Wong, Alice P S Kong, Joseph Jao-Yiu Sung, Alfred Sze-Lok Cheng*. Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver. Cell Mol Immunol.2022;19(7):834-847. doi: 10.1038/s41423-022-00872-3.
8. Feng Yang, Can Xu, Chunhong Li, Xinni Xiang, Yi Zhao, Cong Hu, Huan Rong, Yu He, Jingyu Li, Yu Wang, Chao Tang, Xiaoyu Liu, Renyan Li*, Fei Deng*, Tingxiu Xiang*. Amplification-free cancer diagnosis based on inhibition of Cas12a activity by site-specific 5mC-modified cfDNA. Nucleic Acids Res. 2025;53(22):gkaf1383. doi: 10.1093/nar/gkaf1383.
9. Zhewen Xiong, Stephen Lam Chan, Jingying Zhou, Joaquim S L Vong, Tsz Tung Kwong, Xuezhen Zeng, Haoran Wu, Jianquan Cao, Yalin Tu, Yu Feng, Weiqin Yang, Patrick P C Wong, Willis W Y Si-Tou, Xiaoyu Liu, Jing Wang, Wenshu Tang, Zhixian Liang, Jiahuan Lu, Ka Man Li, Jieting Low, Michael W Y Chan, Howard H W Leung, Anthony WH Chan, Ka-Fai To, Kevin Y L Yip, Yu Ming Dennis Lo, Joseph Jao-Yiu Sung*, Alfred Sze-Lok Cheng*. Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma. Gut. 2023;72(9):1758-1773. doi: 10.1136/gutjnl-2022-328364. Epub 2023 Apr 5. PMID: 37019619; PMCID: PMC10423534.
10. Renjie Yu, Xi Peng, Zhaobo Cheng, Yue Wu, Huan Rong, Lin Yi, Jing Ran, Chaoqun Deng, Xiangyi Zhou, Ruijie Ming, Ningning Zhang, Xiaoyu Liu, Xiaohua Zeng, Yun Xiao, Xue Wang, Yongzhong Wu, Bo Qin, Tingxiu Xiang. Promoter Hyper-methylation of ZNF662 Restrains its Tumor Suppressing Function in Triple-Negative Breast Cancer Through Regulating NGF Signaling Axis. Int J Biol Sci. 2025;21(9):4081-4097. doi: 10.7150/ijbs.102940.
二、相关奖励与荣誉
[1] 2025重庆市医学英语竞赛决赛一等奖
[2] 2021 GUT-IDDF Young Investigator Award
[3] 2020 Japanese Cancer Association Travel Grant Award
