1. 2024.01-至今 重庆大学附属人民医院 主治医师/中心实验室PI
2. 2019.09-2023.10 Technical University of Dresden, Faculty of Medicine, Carl Gustav Carus, Germany德累斯顿工业大学卡尔古斯塔夫克鲁斯医院Anesthesiology and Intensive therapy麻醉与危重症医学系 博士学习
3. 2018.12 – 2019.09 Technical University of Dresden, Faculty of Medicine, Carl Gustav Carus, Germany德累斯顿工业大学卡尔古斯塔夫克鲁斯医院Anesthesiology and Intensive therapy麻醉与危重症医学系 访问学者
4. 2018.09 – 2018.11重庆市人民医院重症医学科 主治医师
5. 2018.06 -2018.08 Technical University of Dresden, Faculty of Medicine Carl Gustav Carus, Germany德累斯顿工业大学卡尔古斯塔夫克鲁斯医院Anesthesiology and Intensive therapy麻醉与危重症医学系 访问学者
6. 2017.09 -2018-02重庆市人民医院重症医学科 主治医师
7. 2017.06 – 2017.08 Linköping University Hospital, Sweden.瑞典林雪平大学附属医院,Heart Center心脏中心 访问学者
8. 2016.03 – 2017.05重庆市人民医院重症医学科 主治医师
9. 2013.07 – 2016.02重庆市中山医院重症医学科 主治医师(2015年起任科副主任)
10. 2007.07 – 2009.09第三军医大学附属大坪医院(现中国人民解放军陆军特色医学中心),野战外研所重症医学科 医师
一、文章
1.Ran Xi, Scharffenberg M, Wittenstein J, et al.Induction of subject-ventilator asynchrony by variation of respiratory parameters in a lung injury model in pigs[J]. Respiratory Research, 2024, 25(1): 358.
2.Ran, Xi, Sabine Müller, Robert Huhle, Martin Scharffenberg, Christian Schnabel, Marcelo Gama de Abreu, Jorge Ferreira, and Jakob Wittenstein."Modulation of the hippo-YAP pathway by cyclic stretch in rat type 2 alveolar epithelial cells—a proof-of-concept study." Frontiers in Physiology 14 (2023): 1253810.
3.Wittenstein, Jakob, Martin Scharffenberg, Xi Ran, Diana Keller, Pia Michler, Sebastian Tauer, Raphael Theilen et al."Comparative effects of flow vs. volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in pigs." Intensive Care Medicine Experimental 8 (2020): 1-16.
4.Wittenstein, Jakob, Martin Scharffenberg, Xi Ran, Yingying Zhang, Diana Keller, Sebastian Tauer, Raphael Theilen et al."Effects of body position and hypovolemia on the regional distribution of pulmonary perfusion during one-lung ventilation in endotoxemic pigs." Frontiers in Physiology 12 (2021): 717269.
5.Scharffenberg, Martin, Jakob Wittenstein,Xi Ran, Yingying Zhang, Anja Braune, Raphael Theilen, Lorenzo Maiello et al."Mechanical power correlates with lung inflammation assessed by positron-emission tomography in experimental acute lung injury in pigs."Frontiers in Physiology 12 (2021): 717266.
6.Zhang, Y., Wittenstein, J., Braune, A., Theilen, R., Maiello, L., Benzi, G., Bluth, T., Kiss, T., Ran, X., Koch, T. and Rocco, P.R., 2024.Mechanical power is associated with cardiac output and pulmonary blood flow in an experimental acute respiratory distress syndrome in pigs. Frontiers in physiology, 15, p.1462954.
二、承担和参与的科学研究项目
1)重庆市科技局自然科学基金,机械能在人机异步导致的呼吸机相关性肺损伤中的呼吸力学机制研究(2024NSCQ-MSX4237),项目负责人(2024.07.-2027.06)
2)重庆市科卫联合医学科研项目面上项目,基于PPG和AI融合无创监测系统开发及在机械通气的临床应用研究(2026MSXM008),项目负责人(2026.01-2027.12)
3)重庆市教委青年基金,基于程控的波形高仿真可控式人机异步大动物模型的建立及呼吸力学机制研究(KJQN202400124),项目负责人(2024.09-2027.10)
4)Faculty of Medicine Carl Gustav Carus, TU Dresden,Germany德国德累斯顿工业大学卡尔古斯塔夫克鲁斯医学院Meddrive基金Modulation of the Hippo-YAP pathway in the alveolar epithelium by dynamic cell stretch – a proof-of-concept study(60510),研究骨干(2022-01至2022-12)
5)Deutsche Forschungsgemeinschaft德国国家科学基金委DFG医学研究项目, Distribution of mechanical energy intensity during mechanical ventilation: An investigation on the mechanisms of ventilator induced lung injury(GA 1256/8-1),研究骨干(2020-11至2022-10)
6)ESAIC Research Support Grant 2020欧洲麻醉与危重症学会支持基,Intensity of energy during mechanical ventilation – A proof-of-concept pilot experimental study on the mechanisms of ventilator-induced lung injury.研究骨干(2020-01至2024-01)
三、相关奖励与荣誉
1)2020年 德国sächsische landesstipendie奖学金
2)2016-2017年度重庆市人民医院优秀科室主任
3)2015-2016 年度重庆市人民医院最优秀医师