1.文章
1.Yan, L., Z. Wang, Y. Yin, C. Niu*and Y. Luo, Coupling enzymatic digestion with nanopore sensing for low-abundance EGFR-L858R mutation detection. Front Bioeng Biotechnol, 2025. 13: p. 1602494.
2.Yan, G., Z. Hu, Y. Peng, Y. Tu, J. Xie, Y. Zhong, C. Niu and Y. Luo, Exposure to bacterial lipopolysaccharide aggravates H1N1-mediated lung immunopathology via neutrophil extracellular trap formation. Sci Rep, 2025. 15(1): p. 40541.
3.Hu, Q., X. Cheng, Y. Lan, H. Lei, C. Niu**and Y. Luo, Serum uric acid predictive value and prognostic impact in rheumatoid arthritis' associated interstitial lung disease. Front Med (Lausanne), 2025. 12: p. 1623557.
4.Guo, Y., K. Shen, Z. Li, C. Niu* and Y. Luo, MiR-147b-3p promotes osteogenesis by targeting NDUFA4 and PI3K/AKT pathway. J Orthop Surg Res, 2025. 20(1): p. 235.
5.Du, C., Q. Liu, Y. Guo, J. Gong, L. Yan, Z. Li and C. Niu*, Prediction of Lung Cancer Metastasis Using Machine Learning Models Based on Clinical Laboratory Data. Cancer Rep (Hoboken), 2025. 8(10): p. e70350.
6.Xiao, Y.H., Y.L. Hu, X.Y. Lv, L.J. Huang, L.H. Geng, P. Liao, Y.B. Ding and C.C. Niu*, The construction of machine learning-based predictive models for high-quality embryo formation in poor ovarian response patients with progestin-primed ovarian stimulation. Reprod Biol Endocrinol, 2024. 22(1): p. 78.
7.Wan, Y., Y. Zhang, T. Li, S. Chen and C. Niu*, Prediction the Occurrence of Thalassemia With Hematological Phenotype by Diagnosis of Abnormal HbA1c. J Clin Lab Anal, 2024. 38(19-20): p. e25104.
8.Ji, X., C. Yang and C. Niu*, Proteomic and metabolomic exploration in relapse acute myeloid leukemia bone marrow supernatant combined with genetic characteristics. BMC Cancer, 2024. 24(1): p. 1545.
9.Zhang, Z., Z. Yang, X. Xiang, P. Liao and C. Niu*, Mutation of TonB-Dependent Receptor Encoding Gene MCR_0492 Potentially Associates with Macrolides Resistance in Moraxella catarrhalis Isolates. Infect Drug Resist, 2022. 15: p. 2419-2426.
10.Niu, C.*, D. Wu, A.J. Li, K.H. Qin, D.A. Hu, E.J. Wang, A.B. Tucker, F. He, L. Huang, H. Wang, Q. Liu, N. Ni, D. Shi, X. Zhao, Y. Wan, T. Li, T. He and P. Liao, Identification of a prognostic signature based on copy number variations (CNVs) and CNV-modulated gene expression in acute myeloid leukemia. Am J Transl Res, 2021. 13(12): p. 13683-13696.
11.Lei, H.X., C.C. Niu*, T. Li, Y.F. Wan, W.B. Liang, R. Yuan and P. Liao, A Novel Electrochemiluminescent Immunoassay Based on Target Transformation Assisted with Catalyzed Hairpin Assembly Amplification for the Ultrasensitive Bioassay. ACS Appl Mater Interfaces, 2019. 11(34): p. 31427-31433.
12.Niu, C.C.*, Y.F. Wan, C. Yang, T. Li and P. Liao, Polymorphisms of the CYR61 gene in patients with acute myeloid leukemia in a Han Chinese population. Medicine (Baltimore), 2018. 97(34): p. e11963.
13.Li, L., C. Niu*, T. Li, Y. Wan, Y. Zhou, H. Wang, R. Yuan and P. Liao, Ultrasensitive electrochemiluminescence biosensor for detection of laminin based on DNA dendrimer-carried luminophore and DNA nanomachine-mediated target recycling amplification. Biosens Bioelectron, 2018. 101: p. 206-212.
14.Niu, C.C.*, C. Zhao, Z. Yang, X.L. Zhang, J. Pan, C. Zhao and W.K. Si, Inhibiting CCN1 blocks AML cell growth by disrupting the MEK/ERK pathway. Cancer Cell Int, 2014. 14: p. 74.
15.Niu, C.C.*, C. Zhao, X.L. Zhang, J. Pan, C. Zhao, W.R. Wu, Z.Q. Li, T. Liu, Z. Yang and W.K. Si, Wnt5a enhances the response of CML cells to Imatinib Mesylate through JNK activation and γ-catenin inhibition. Leuk Res, 2013. 37(11): p. 1532-7.
16.Niu, C.C.*, C. Zhao, Z.D. Yang, X.L. Zhang, W.R. Wu, J. Pan, C. Zhao, Z.Q. Li, W. Ding, Z. Yang and W.K. Si, Downregulation of γ-catenin inhibits CML cell growth and potentiates the response of CML cells to imatinib through β-catenin inhibition. Int J Mol Med, 2013. 31(2): p. 453-8.
2.专利
(1)一种用于筛查急性髓系白血病的引物、试剂盒和方法,ZL 201810941885.3,2022.3.29 第一发明人;
(2)用于CCN1蛋白的电化学发光检测的生物传感器及其制备方法和应用,ZL 201910534579.2,2021.9.10,第一发明人。
3.项目
(1)重庆市技术创新与应用发展专项重点项目,检验医学大数据智慧应用关键技术研发;项目负责人
(2)重庆市科卫联合医学科研项目面上项目,基于骨髓微环境多组学特征与机器学习的急性髓系自血病预后模型建立与评价;项目负责人
(3)国家自然科学基金委员会, 青年科学基金项目,基于金磁颗粒及核酸扩增策略的高性能蛋 白检测技术建立及其在CCN1蛋白检测中的应用研究;项目负责人
(4)重庆市科学技术局, 重庆市自然科学基金面上项目CCN1信号网络DNA拷贝 数变异作为急性髓系白血病分子生物标志物的临床诊断价值与机制研究;项目负责人
(5)重庆市科学技术委员会, 重庆市基础与前沿研究计划, CCN1 基因单核苷酸多态 性与急性髓系白血病相关性的研究;项目负责人