1. 2025.10-至今,重庆大学附属三峡医院,副主任医师
2. 2023.10-2025.09,中南大学湘雅医院康复医学科,副主任医师
3. 2015.10-2023.09,中南大学湘雅医院康复医学科,主治医师
4. 2011.08-2015.09,中南大学湘雅医院康复医学科,医师
成果:发表中英文论文20余篇;专著1部;主持省部级及以上项目3项,参与国家重点研发计划等多项课题。
代表性论文:
1. Orally deliverable chitosan/lecithin nanoparticles enhance baicalin bioavailability to activate gut-brain FXR-Trem2 signaling and reprogram neuroenergetics in ischemic stroke therapy. Chemical Engineering Journal, 2026.(JCR 一区,第一作者) IF13.2
2. From the Gut to the Brain: Microplastic-Associated Neurovascular Dysfunction and Implications for Stroke Risk. Advanced Science, 2026.(JCR 一区,第一作者)IF14.1
3. Therapeutic Targeting of the IRF9/RTN4/RHOA/ROCK Pathway via RVG29-Modified PLGA Nanoparticles and rTMS for Neural and Vascular Regeneration Post-Cerebral Infarction. Advanced Healthcare Materials, 2025.(JCR 一区,通讯作者)IF9.6
4. Trends and Future Projections of Neurological Disorder Burden in Europe, 1990-2021: Latest Insights from the GBD 2021 Study. Neuroepidemiology, 2025.(JCR 一区,通讯作者)IF4.0
5. Predictive value of early serum ACSL4 and ASITN/SIR grade for motor function recovery in patients with post-ischemic stroke lower limb neurological sequelae after modified constraint-induced movement therapy. Clinical Neurology and Neurosurgery, 2024.(JCR 二区,通讯作者)
6. Utilizing network pharmacological analysis to investigate the key targets and mechanisms of kaempferol against oxaliplatin-induced neurotoxicity. Toxicology Mechanisms and Methods, 2022.(JCR 二区,第一作者)
著作:
1. 《神经重症诊治与监护技术》,第一副主编,吉林科学技术出版社,2019年。
主持项目:
1. 国家自然科学基金地区基金项目,82260455,PirB基因调控脑梗死后CIMT诱导的脑可塑性的机制研究,2023.01-2026.12,32万元,主持。
2. 湖南省自然科学基金企业联合基金项目,2025JJ90276,RVG29-PEG-PLGA纳米粒子递送siRNA抑制ATX蛋白表达改善脑梗死后重复经颅磁刺激(rTMS)疗效的作用机制研究,2025.01-2027.12,5万元,主持。
3. 新疆维吾尔自治区自然科学基金面上项目,2021D01C366,PirB基因沉默对脑梗死后CIMT诱导的活动依赖可塑性的影响,2021.06-2024.05,7万元,主持