1.文章：(近五年以第一作者或通讯作者发表的文章）
(1)Yu W, Chen Z, Wu B, Zhang C, Han Y, Zou D, Zhang J,Wu N.Modular nanotherapeutics with spatiotemporal precision for phase-specific treatment of intracerebral hemorrhage. Bioact Mater. 2025 Dec 12;58:331-347. doi: 10.1016/j.bioactmat.2025.12.007.IF: 20.3 Q1 .
(2)Wu B, Yu W, Zhang G, Jiang H, Wu N. Triglyceride-glucose index: a novel assessment tool for all-cause mortality in critical stroke patients-a retrospective analysis of the eICU-CRD database. Cardiovasc Diabetol. 2025 Jul 26;24(1):304. doi: 10.1186/s12933-025-02872-9. IF: 10.6Q1
(3)Wang P, Liao B, Gong S, Guo H, Zhao L, Liu J, Wu N. Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1α/HIF2α regulation. Cell Death Dis. 2025 Apr 19;16(1):317. doi: 10.1038/s41419-025-07617-wIF:9.6Q1
(4)Xu C, Shao C, Jiang H, Zeng C, Zhang G, Li X, Shen Y, Yalikun Y, Li M, Liu X, Wu N, Tang T. Ring-Shaped Open Microfluidic Platform Reveals Viscosity-Driven Mechanical Priming of Glioblastoma Cells. ACS Sens. 2025 Dec 26;10(12):9457-9466. doi: 10.1021/acssensors.5c02716.IF:9.6Q1
(5)Wang P, Gong S, Liao B, Liu J, Zhao L, Wu N. HIF-1α and HIF-2α: synergistic regulation of glioblastoma malignant progression during hypoxia and apparent chemosensitization in response to hyperbaric oxygen. Cancer Cell Int. 2025 Jul 3;25(1):251. doi: 10.1186/s12935-025-03823-wIF: 6.0 Q1
(6)Qiao N, Gao W, Deng X, Xin T, Zhang G,Wu N,etc.Combined simultaneous transsphenoidal and transcranial regimen improves surgical outcomes in complex giant pituitary adenomas: a longitudinal retrospective cohort study. Int J Surg. 2024 Jul 1;110(7):4043-4052. IF:12.5 Q1
(7)Xu Chao#, Wang Pan#, Guo Haiyan, et al. MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway. Cell death discovery. 2023,9:206. IF=7.00
(8)Wang P, Gong S, Liao B, Liu J, Zhao L, Yao H, Wu N. miR-652-5p promoter hypermethylation enhances glioblastoma malignancy through the SDC1/TGFβ2/pERBB4 complex via HIF2α-mediated regulation under hypoxia. Cancer Cell Int. 2025 Dec 20. doi: 10.1186/s12935-025-04122-0. IF: 6.0 Q1
(9)Wu B, Yu W, Zhang G, Jiang H, Chen Y, Wu N. Mining the risk factors for stroke occurrence and dietary protective factors based on the NHANES database: Analysis using SHAP. J Affect Disord. 2025 Jun 14;389:119671. doi: 10.1016/j.jad.2025.119671IF: 4.9 Q1 . Epub ahead of print. PMID: 40516626IF: 4.9 Q1
(10)Liao B, Wang P, Gong S, Zhao L, Liu J, Wu N. Coordinated regulation of IGF1R by HIF1αand HIF2αenhances chemoresistance in glioblastoma. Front Pharmacol. 2025 Apr 11;16:1575332. doi: 10.3389/fphar.2025.1575332. PMID: 40290443; PMCID: PMC12021886. IF:4.8Q1
(11)Gong S, Wang P, Liao B, Zhao L, Wu N. Hyperbaric oxygen promotes both the proliferation and chemosensitization of glioblastoma cells by inhibiting HIF1α/HIF2α-ABCG2. Front Mol Neurosci. 2025 Apr 30;18:1584407. doi: 10.3389/fnmol.2025.1584407 IF: 3.8Q2
(12)Pan Wang#; Lu Zhao#; Sheng Gong; Shuanglong Xiong; Junwei Wang; Dewei Zou; Jinyu Pan; Yangmin Deng; Qian Yan; Nan Wu*; Bin Liao*; HIF1α/HIF2α-Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR-PI3K/AKT signalling pathway with positive feedback under hypoxia, CellDeathand Disease, 2021, 12(4):312.IF=8.469 Q1
(13)Pan Wang#; Qian Yan#; Bin Liao; Lu Zhao; Shuanglong Xiong; Junwei Wang; Dewei Zou; Jinyu Pan; Liangqi Wu; Yangmin Deng; Nan Wu*; Sheng Gong*; The HIF1α/HIF2α-miR210-3p network regulates glioblastoma cell proliferation, dedifferentiation and chemoresistance through EGF under hypoxic conditions,CellDeathand Disease, 2020, 11(11):992. IF=8.469 Q1
(14)Pan Wang#, Sheng Gong#, Jinyu Pan, Junwei Wang, Dewei Zou, Shuanglong Xiong, Lu Zhao, Qian Yan, Yangming Deng, Nan Wu* and Bin Liao*. Hyperbaric oxygen promotes not only glioblastoma proliferation but alsochemosensitization by inhibiting HIF1α/HIF2α-Sox2, Cell death discovery, 2021, 7:103.IF=5.241
(15)Pan Wang, Sheng Gong, Bin Liao, Jinyu Pan, Junwei Wang, Dewei Zou, Lu Zhao, ShuanglongXiong, Yangmin Deng, Qian Yan, Nan Wu.HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions ,Journal of Cancer,2022,13(1): 1-14. IF=4.478
(16)HAO TIANJIANG, PAN WANG, DE WEI ZHOU, LONG WEI ZENG, BO LIN and NAN WU*.Fully endoscopic microvascular decompression for hemifacial spasm,Experimental and Therapeutic Medicine,2022,24(1):483. IF=2.751
(17)CHAO XU,PAN WANG,JUNWEI WANG,WUJUN FENG and NAN WU*. Middle cranial fossa trigeminal schwannoma resection through endoscopic transnasal maxillary sinus approach: A case report and literature review,EXPERIMENTAL AND THERAPEUTIC MEDICINE,2022,23;405. IF=2.751
(18)Chuan Shao,Tang H, Wang X, He J, Wang P,Nan Wu*.Body mass index and glioma risk: A prospective multicenter study,Front Endocrinol (Lausanne),2022;13:933921.IF=6.58
(19)Chuan Shao,Tang H, Wang X, He J, Wang P,Nan Wu*.Oral Contraceptive and Glioma Risk: A Prospective Cohort Study and Meta-Analysis,Front Public Health,2022;10:878233. IF=6.46
(20)Chuan Shao,Wang X, Wang P, Tang H, He J,Nan Wu*.Parkinson's Disease Risk and Alcohol Intake: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies,FrontiersinNutrition,2021;8:709846. IF=6.06
(21)Haotian Jiang,Dewei Zhou,Pan Wang,Longwei Zeng, Jie Liu,Chao Tang,Gang Zhang, Xiaorong Tan and Nan Wu*Case report: Fully endoscopic microvascular decompression for glossopharyngeal neuralgia.Frontiers in Surgery,2023 11;13:1090478.IF=2.568
(22)Haotian Jiang,Dewei Zou,Pan Wang,Longwei Zeng, Jie Liu,Chao Tang,Gang Zhang, Xiaorong Tan and Nan Wu*Case report: Fully endoscopic microvascular decompression for trigeminal neuralgia.Frontiers in Neurology,2023,6;9:1089632. IF=4.086
(23)CHAOTANG, PAN WANG, JIE LIU, HAOTIAN JIANG, GANG ZHANG and NAN WU*.Endoscopic endonasal transsphenoidal approach for symptomatic Rathke cleft cyst: A case series.EXPERIMENTAL AND THERAPEUTIC MEDICINE,2022,24(6):713. IF=2.751
(24)Zhang G, Jia B, Wang P, Xu C, Liu J, Tang C, Jiang H, Tan X, Wu N*. Pure endoscopic minimally invasive surgery with a non‑expandable tubular retractor for intradural extramedullary spinal tumors.EXPERIMENTAL AND THERAPEUTIC MEDICINE,2023,25(3):137.IF=2.751
(25)Jie Liu, Pan Wang, Chao Tang, Haotian Jiang, Gang Zhang, Nan Wu*.Endoscopic endonasal transsphenoidal approach for craniopharyngioma: A case report. EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2023, 25(3): 114.Q3 IF=2.7
(26)CHAO TANG, JUN WEI WANG, PAN WANG, DE WEI ZOU and NAN WU*.Staged surgery for irregular giant pituitary adenomas: A report of two cases.OncologyLetters,2023, 25(3): 118.Q4 IF=3.111
(27)HAO TIAN JIANG,PAN WANG,DE WEI ZHOU,LONG WEI ZENG,BO LIN and NAN WU*. Comparison of supraorbital keyhole approach and extended transsphenoidal approach in endoscopic surgery for tuberculum sellae meningioma: A case series,EXPERIMENTAL AND THERAPEUTIC MEDICINE,2023,25:215.Q4 IF=2.751
(28)Shao C#, Wang P, Liao B, Gong S, Wu N*. Multi-Omics Integration Analysis of TK1 in Glioma: A Potential Biomarker for Predictive, Preventive, and Personalized Medical Approaches. Brain Sci. 2023;13(2):230. Q3 IF=3.333
(29)Zhang G#, Wang P, Wang J, Zou D, Yao H, Liu J, Tang C, Jiang H, Tan X and Wu N*Endoscopic endonasal surgery for non-invasive pituitary neuroendocrinology tumors with incomplete pseudocapsule.Frontiers in Neurology. 2023;14:1109388 Q2 IF=4.086
(30)HAO TIAN JIANG, PAN WANG,JUN WEI WANG,JIE LIU,CHAO TANG,GANG ZHANG,JIN YU PAN, HAO FEI GENG and NAN WU*,Endoscopic transsphenoidal approach in resection of intracranial clivus chondrosarcoma: A case report,ONCOLOGY LETTERS，2023, 26: 498.IF=2.9
(31)Jie Liu,Pan Wang,Hua Zhang,Nan Wu*,Distinguishing brain tumors by Label-free confocal micro-Raman spectroscopy，Photodiagnosis and Photodynamic Therapy，2024（45）10401
(32)Jie Liu, Pan Wang, Jun wei Wang, Gang Zhang, Hao tian Jiang, Xiaorong Tan, Nan Wu*, Malignant Melanoma of the Sphenoid Sinus: Case Report and Literature Review. Ear Nose Throat J. 2024 May 29:1455613241256520.IF: 1.0 Q3
(33)Jie Liu, Junwei Wang, Pan Wang, Nan Wu. Extended Endoscopic Transsphenoidal Surgery with Total Cyst Wall Decollement for Suprasellar Cystic Craniopharyngioma: Case Report and Literature Review. Ear Nose Throat J. 2024 Oct 15:1455613241291744.IF: 1.0 Q3 .
(34)Jie Liu, Pan Wang, Hua Zhang, Yuansen Guo, Mingjie Tang, Junwei Wang, Nan Wu*. Current research status of Raman spectroscopy in glioma detection. Photodiagnosis Photodyn Ther. 2024 Oct 24:104388. doi: 10.1016/j.pdpdt.2024.104388. IF:3.1 Q2 2024.10.24
(35)Shao C, Wang J, Wang P,Wu N*.A novel multilayered membrane repair technique for high-flow cerebrospinal fluid leaks during expanded endoscopic endonasal tumor resection. Am J Transl Res. 2024 Nov 15;16(11):6753-6757. IF1.7
(36)Pan J, Shao C, Tang H, Wu N. Coffee and tea consumption and glioma risk: a meta-analysis of cohort studies. Front Nutr. 2024 Dec 16;11:1506847.IF: 4.0 Q2.
(37)Liu L, Shao C, Li L, Wu N. Endometriosis and Mortality Risk in US Women: Findings From NHANES 1999-2006. Int J Womens Health. 2025 Jul 22;17:2233-2244. doi: 10.2147/IJWH.S530529 IF: 2.6 Q1
(38)Shao C, Zou D, Wang J, Lai J, Wu N. Pituitary apoplexy in a patient on antiplatelet therapy: A case report. Exp Ther Med. 2025 Apr 24;29(6):124. doi: 10.3892/etm.2025.12874IF: 2.3 Q3 . PMID: 40357312 IF: 2.3 Q3; PMCID: PMC12067521 IF: 2.3 Q3
(39)Pan J, Shao C, Xu C, Zhang G, Jiang H, Tang T, Tang H, Wu N. Association between hormone therapy and glioma risk in US women: a cancer screening trial. Menopause. 2025 Apr 1;32(4):346-352. doi: 10.1097/GME.0000000000002507 . IF: 3.0 Q1.
(40)Gong S, Wang P, Liao B, Zhao L, Wu N. Hyperbaric oxygen promotes both the proliferation and chemosensitization of glioblastoma cells by inhibiting HIF1α/HIF2α-ABCG2. Front Mol Neurosci. 2025 Apr 30;18:1584407. doi: 10.3389/fnmol.2025.1584407 IF: 3.8 Q2 .
(41)Jiang H, Zou D, Shao C, Wu N. Fully endoscopic microvascular decompression for painful tic convulsif secondary to vertebrobasilar dolichoectasia. Am J Transl Res. 2025 May 15;17(5):3824-3829. doi: 10.62347/URCV2139 IF: 1.6 Q3 .
(42)Wan W, Wang P, Liao B, Zhao L, Gong S, Wei L, Wu N. Single-cell mapping of TMZ-resistant glioma reveals CXCL2/3-CXCR2-associated neutrophil communication. Biochem Biophys Res Commun. 2025 Oct 20;785:152706. doi: 10.1016/j.bbrc.2025.152706IF: 2.2 Q3 . Epub 2025 Sep 25. PMID: 41016335IF: 2.2 Q3 .
(43)汪攀；HIF2α调控miR-652-5p启动子甲基化促进胶质母细胞瘤细胞侵袭及化疗抵抗，中华神经外科杂志2025第9期943-951。
(44)蒋皓天；汪攀；廖彬；龚胜；吴南*生长激素对结肠癌细胞侵袭和迁移的影响，重庆医学2024年3月第53卷第5期。
(45)张港；汪攀；廖彬；龚胜；吴南*PIK3R3在生长激素型垂体神经内分泌肿瘤中的表达及其生物学功能研究，中华神经外科杂志,2024,40(6):618-625
(46)谭筱蓉；徐超；汪攀；吴南*；MiR-4488靶向SCRT1调控胶质母细胞瘤细胞的迁移和侵袭，重庆医学，2025年4月第54卷第4期4。
(47)刘杰，汪攀，汤超，张华，吴南*; 激光共聚焦显微拉曼光谱在鉴别垂体腺瘤分泌类型中的应用,中华神经外科杂志, 2023, 39(4): 356-361 (CSCD)
(48)龚胜；汪攀；廖彬;赵璐;吴南；缺氧诱导因子1α经多配体蛋白聚糖1调控缺氧胶质瘤细胞增殖及替莫唑胺抵抗机制初探,中华神经外科杂志, 2023, 39(10): 1035-1043.
(49)汪攀;廖彬;龚胜;赵璐;王俊伟;邹德伟;吴南*;缺氧诱导因子1α与２α在胶质瘤细胞增殖及化疗抵抗中的协同调控作用,中华神经外科杂志,2021,37(6):605-611.
2.专利：（以第一发明人发明的专利 ）
(1)经鼻神经颅底修复装置、颅底修复膜及其装置的使用方法,发明专利，发明人：吴南;汪攀;王俊伟;邹德伟;潘金玉，专利号：ZL 2021 1 1446849.8 授权公告日：2025年04月04日
(2)一种用于经鼻内镜颅底手术的可伸缩刮匙及其使用方法，发明专利，发明人：吴南;汪攀;王俊伟;邹德伟;潘金玉，专利号：ZL 2022 1 1110694.5 授权公告日：2024年11月01日
(3)经鼻神经颅底修复装置及颅底修复膜，实用新型，发明人：吴南、汪攀、王俊伟、邹德伟、潘金玉，专利号：ZL 2021 2 2981046.4 授权公告日：2022.07.19
(4)一种可伸缩刮匙，实用新型，发明人：吴南、汪攀、王俊伟、邹德伟、潘金玉，专利号：ZL 2022 2 2418234.0 授权公告日：2023.03.24
3.项目：（主持项目）
(1)国家自然科学基金面上项目，HIF2α经miR-652-5p启动子甲基化促进胶质瘤细胞SDC1/TGFβ2表达进而化疗抵抗分子机制研究，82473430，2025.01.01-2027.12.31，主持，49万元。
(2)国家重点研发计划项目子课题，2016YFC0101004，太赫兹波精准脑外科手术在体成像系统的研发-医学验证与临床应用方案研究，2016.07-2018.12，235万元，主持。
(3)重庆市医学科技创新专病医学研究中心“重庆市脑胶质瘤精准医学研究中心”，2023.01.01-2025.12.31，270万元，主持。
(4)2022年重庆市科卫联合医学科研重大项目高压氧联合替莫唑胺治疗恶性脑胶质瘤多中心、随机对照、前瞻性临床研究2023DBXM004，2023.01.01-2025.12.31，200万元，主持。
(5)国家自然基金面上项目, 81672493, PTEN/PI3K信号通路经HIF1a/ABCG2蛋白介导胶质 瘤高压氧化疗增敏分子机制研究，2017/01-2020/12，50万元，主持。
(6)重庆市自然科学基金面上项目，cstc2021jcyj-msxmX0686，HIF1α经miR-652-5p启动子甲基化促进TGFβ2表达诱导胶质瘤细胞亚剂量化疗后逆分化分子机制研究，15万元2021.10-2024.09，主持。
(7)2021年重庆市技术创新与应用发展专项重点项目，基于光谱显微技术和卷积神经网络深度学习的脑胶质瘤分子分型模型体系构建研究，2022.01-2024.12，100万元，主持。
(8)2021年重庆英才·创新领军人才项目，80万元，负责人
(9)国家自然科学基金面上项目，81272784，HIF1a-Notch1通路在缺氧诱导胶质瘤逆分化为肿瘤干样 细胞中的作用及机制研究，2013/01-2016/12，70万元，主持。
(10)国家卫生部课题，W2011BX036，瘤内免疫靶向放疗联合光动力治疗脑胶质瘤的临床 研究，2010/01-2013/12，30万元，主持。
(11)国家自然科学基金面上项目，30872660，国人汉语感觉性语言区fMRI与MEG脑功能成像特点及脑胶 质瘤对其的影响，2009/01-2011/12，32万元，主持。
(12)国家科技支撑计划，2007BAI05B08，脑肿瘤的早期影像学诊断及疗效评估，2008/01 -2010/12，4万元，主持。
(13)重庆市自然基金，CSTC2007BB5043，国人汉语语言区脑功能成像特点的初步研究，2 007/07-2009/12，3万元，主持。
(14)第三军医大学第一附属医院重大领域技术创新项目,SWH2016ZDCX2004,复杂颅底肿瘤经鼻神经内镜手术后的颅底重建技术,2016.12-2019.11，50万元，主持。
(15)第三军医大学第一附属医院“军事医学科技创新计划”，SWH2016LHJC-04，太赫兹波谱成像技术在早期脑缺血检测中的研究，2016.10-2018.10，40万元，主持。
4.获奖：（科技奖励）
(1)吴南（排名第1), 新型多模态物理技术在脑胶质瘤精准诊治中的创用，重庆市科技进步奖一等奖，2019
(2)吴南(排名第1), 难治性癫痫致痫灶精准定位体系建立与微创手术，中国人民解放军总后勤部医疗成果奖二等奖，2014.10
(3)吴南（排名第3），神经肿瘤微创诊治的临床与基础研究，重庆市科技进步奖一等奖，2010(2011.05)
(4)吴南（排名第2），磁共振脑功能导航在脑外科手术中的应用，中国人民解放军总后勤部医疗成果奖三等奖，2009.9
(5)吴南（排名第8），神经肿瘤的个性化微创治疗，中国人民解放军总后勤部医疗成果奖二等奖，2008
(6)吴南（排名第2），脑立体定向微创手术及相关技术的应用研究，重庆市科技进步奖二等奖，2005(2006.3)
学术任职：
中国医师协会神经外科医师分会常委
中国医学装备协会神经外科分会常委
中国老年学会神经外科专委会常委
重庆市中西医结合学会神经外科专委会主任委员
重庆市医学会神经外科分会副会长
中国医师协会中国医师协会神经外科专委会委员
中国医促会神经外科分会委员
中国垂体腺瘤专家委员会委员
中国垂体腺瘤协作组常务委员
