重庆大学附属人民医院中医科主任/副教授
联系方式：19112090082
邮箱：jinwei.zhang@cqu.edu.cn
学习经历
2016.09-2019.06 广州中医药大学 中西医结合 医学博士
2013.09-2016.08 广州中医药大学 中西医结合 医学硕士
2008.09-2013.08 河北医科大学 中医学 医学学士
工作经历
2024.04-今 重庆市人民医院 科室主任/副教授
2024.01-2024.03 重庆市中医院 副教授
2020.09-2023.12 重庆市中医院 主治医师
2019.07-2020.08 重庆市中医院 住院医师
研究方向
(1) 皮肤及其附属器的病理机制研究;
(2) 中西医结合治疗皮肤及其附属器疾病机制研究
招生资格：硕士研究生导师
成果：
1.文章
[1] Jinwei Zhang, Yue Lu, Jianan Wei, Li Li, Ling Han. Protective effect of carboxytmethylpachymaran on TNF-α-induced damage in Caco-2 cell monolayers[J]. International Journal of Biological Macromolecules, 2016(93): 506-511.
[2] Jinwei Zhang, Xiong Li, Jian'an Wei, Haiming Chen, Yue Lu, Li Li, Ling Han, Chuanjian Lu. Gallic acid inhibits the expression of keratin 16 and keratin 17 through Nrf2 in psoriasis-like skin disease[J]. International Immunopharmacology, 2018(65): 84-95.
[3] Wanqun Chen, Hong Qiu, Xiaojun Yang, Jinwei Zhang. Appendix bleeding with painless bloody diarrhea: A case report and literature review[J]. Open Medicine, 2019(14): 735-739.
[4] Jinwei Zhang, Xiaojun Yang, Hong Qiu, Wanqun Chen. Weight loss may be unrelated to dietary intake in the imiquimod-induced plaque psoriasis mice model[J]. Open Life Sciences, 2020(15): 79-82.
[5] Jinwei Zhang, Hong Qiu, Xiaojing Cao, Ling Han. The Anti-psoriatic Effect of Gallic Acid is Associated with the Suppression of Keratin 6 and Nrf2[J]. Letters in Drug Design & Discovery, 2024(21): 1532-1545.
[6] Weiwei Liu, Jingwei Jiang, Zeming Li, Yang Xiao, Siyi Zhou, Dehuan Wang, Yi Zou, Tiantian Liu, Ke Li, Huan Liang, Nian’ou Wang, Xiao Xiang, Qiaoli Xie, Rixing Zhan, Jinwei Zhang, Xun Zhou, Li Yang, Cheng-Ming Chuong, Mingxing Lei. Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cells[J]. Theranostics, 2024(14): 3339-3357.
[7] Siyi Zhou, Zeming Li, Xinzhu Li, Yuanli Ye, Mengyue Wang, Jingwei Jiang, Lihe Tao, Yan Wang, Chen-Tsen Tung, Yongji Chung, Eunmi Kim, Xinyu Shen, Xuegang Xu, Xiao Xiang, Qiaoli Xie, Jinwei Zhang, Wang Wu, Xia Lin, Cheng-Ming Chuong, Mingxing Lei. Crosstalk between Endothelial Cells and Dermal Papilla Entails Hair Regeneration and Angiogenesis during Aging[J]. Journal of Advanced Research, 2025(70): 339-353.
[8] Shilei Wang, Helin Pan, Chenxi Zhao, Wanqun Chen, Jinwei Zhang. Yinxieling Inhibits Keratin 17 to Enhance Mitochondrial Function and Ameliorates Psoriasis-like Lesions[J]. Current Traditional Medicine, accept.
[9] Wanqun Chen, Jinwei Zhang. Compound Glycyrrhizin Promotes the Transformation of Neutrophils from Pro-Inflammatory to Anti-Inflammatory Effects in Psoriasis Vulgaris[J]. Clinical, Cosmetic and Investigational Dermatology, 2024(17): 2777-2778.
[10] Kangsheng Liao, Ruihong Chen, Jinwei Zhang, Yongdui Ruan, Xueqin Huang, Yuhe Huang, Jiaojiao Xia, Daina Zhao, Lingming Chen, Yi Zhao, Fen Yang, Junfa Xu, Ling Shen, Jiang Pi. cGAS-mediated Antibacterial Immunotherapy Against Tuberculosis by Macrophage-Targeted Manganese Dioxide Nanoagonist[J]. Acta Biomaterialia, 2025, 196(2025)471-486.
[11] Mingxing Lei, Hans I- Chen Harn, Qiwei Li, Jingwei Jiang, Wang Wu, Wei Zhou, Tin- Xin Jiang, Mengyue Wang, Jinwei Zhang, Yung- Chih Lai, Wen-Tau Juan, Randall Bruce Widelitz, Li Yang, Zhong- Ze Gu, Cheng- Ming Chuong. The mechano-chemical circuit drives skin organoid self-organization [J]. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2023, 120(36): e2221982120.
[12] Mengyue Wang, Xun Zhou, Siyi Zhou, Miaomiao Wang, Jingwei Jiang, Wang Wu, Tiantian Liu, Wei Xu, Jinwei Zhang, Deming Liu, Yi Zou, Weiming Qiu, Man Zhang, Weiwei Liu, Zeming Li, Dehuan Wang, Tingting Li, Ji Li, Wanqian Liu, Li Yang, Mingxing Lei. Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development [J]. Theranostics, 2023, 13(9): 2930-45.
[13] Man Zhang, Mengyue Wang, Jingwei Jiang, Weiwei Liu, Siyi Zhou, Dehuan Wang, Miaomiao Wang, Zixian Zhao, Zhiling Xu, Wang Wu, Xia Lin, Jinwei Zhang, Wei Xu, Qu Tang, Wanqian Liu, Li Yang, Xun Zhou, Rixing Zhan, Wei Zhou, Mingxing Lei. COX2-ATP Synthase Regulates Spine Follicle Size in Hedgehogs [J]. International Journal of Biological Sciences, 2023, 19(15): 4763-77.
[14] Mingxing Lei, Jingwei Jiang, Mengyue Wang, Wang Wu, Jinwei Zhang, Wanqian Liu, Wei Zhou, Yung-Chih Lai, Ting-Xin Jiang, Randall B. Widelitz, Hans I-Chen Harn, Li Yang, Cheng-Ming Chuong. Epidermal-dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures [J]. NPJ Regenerative Medicine, 2023, 8(1): 65.
[15] Wang Wu, Wei Zhou, Jingwei Jiang, Mengyue Wang, Jinwei Zhang, Jing Yang, Qu Tang, Huawen Liu, Deming Liu, Wei Xu, Julia Li Zhong, Li Yang, Mingxing Lei. Mechanical stimuli-induced CCL2 restores adult mouse cells to regenerate hair follicles [J]. Molecular Therapy Nucleic Acids, 2023, 32: 94-110.
[16] Lu Yue, Wang Ailin, Zhang Jinwei, Li Leng, Wei Jianan, LiLi, Chen Haiming, Han Ling, Lu Chuanjian. PSORI-CM02 ameliorates psoriasis in vivo and in vitro by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway [J]. Phytomedicine, 2019, 64: 153054.
[17] Yue Lu, Leng Li, Jin-wei Zhang, Xiao-qin Zhong, Jia-nan wei, Ling Han. Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway [J]. World Journal Gastroenterology, 2018, 24(26): 2867-77.
[18] Wan-Qun Chen, Feng-Liang Tian, Jin-Wei Zhang, Xiao-Jun Yang, Yan-Ping Li. Preventive and inhibitive effects of Yiwei Xiaoyu granules on the development and progression of spasmolytic polypeptide-expressing metaplasia lesions[J]. World Journal of Gastrointestinal Oncology, 2021, 13(11), 1741-1754.
[19] Yue Lu, HanJie Lin, JinWei Zhang, JianAn Wei, Jing Sun, Ling Han. Sijunzi Decoction attenuates 2, 4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats and ameliorates TNBS-induced claudin-2 damage via NF-κB pathway in Caco2 cells [J]. BMC Complementary and Alternative Medicine, 2017, 17(1): 35.
2.项目
（1） 国家自然科学基金委员会, 青年科学基金项目，基于AKT-FOXO1通路抑制角蛋白6/16/17研究银屑灵治疗银屑病机制
（2） 国家中医药管理局，中西医协同项目，银屑灵配方颗粒联合复方甘草酸苷注射液治疗2型糖尿病合并银屑病的中西医协同临床研究
（3） 重庆市科学技术委员会，重庆市自然科学基金，基于角蛋白17 破坏线粒体稳态研究清热凉血解毒法治疗寻常型银屑病血热证的机制
（4） 国家中医药管理局，国家中医药传承创新免疫性疾病中心项目，中医药防治自身免疫性疾病
（5） 中华人民共和国科学技术部，重点研发计划，基于光电免疫调控效应的常见慢性皮肤病临床试验研究和应用
